Identification | More | [Name]
2-(4-Chlorophenoxy)-2-methylpropionic acid | [CAS]
882-09-7 | [Synonyms]
2-(4-CHLOROPHENOXY)-2-METHYLPROPANOIC ACID 2-(4-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID 2-(4-CHLOROPHENOXY)ISOBUTYRIC ACID 2-(P-CHLOROPHENOXY)-2-METHYLPROPIONIC ACID 4-CHLOROPHENOXY-ISO-BUTYRIC ACID AKOS B013926 AKOS BB-7852 ALPHA-(P-CHLOROPHENOXY)ISOBUTYRIC ACID ASISCHEM A27485 CLOFIBRIC ACID CLOFIBRINIC ACID RARECHEM AL BO 0794 TIMTEC-BB SBB008306 (Chlorophenoxy)isobutyric acid (p-chlorophenoxy)dimethyl-aceticaci (p-Chlorophenoxy)isobutyric acid 2-(p-chlorophenoxy)-2-methyl-propionicaci 2-(p-Chlorophenoxy)isobutyric acid 4-Chorophenoxy-d-methylpropionicacid 4-CPIB | [EINECS(EC#)]
212-925-9 | [Molecular Formula]
C10H11ClO3 | [MDL Number]
MFCD00004192 | [Molecular Weight]
214.65 | [MOL File]
882-09-7.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36:Wear suitable protective clothing . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
UE9455000
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29189900 |
Hazard Information | Back Directory | [Description]
Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 μM in a transactivation assay) and the active metabolite of clofibrate (Item No. 10956).1 It is formed from clofibrate by tissue and serum esterases.2 Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats.3 It decreases glutamate oxaloacetate transaminase (GOT) levels and increases glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) levels, markers of xenobiotic stress, in the plasma of carp (C. carpio) when administered in tank water at a concentration of 10 μg/L.4 Clofibric acid has been found in wastewater effluent.5 | [Chemical Properties]
Pale Yellow Solid | [Uses]
A hypolipidemic compound | [Uses]
Antilipemic. | [Uses]
herbicide, antihyperlipoproteinemic, antineoplastic | [Definition]
ChEBI: A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate. | [Biological Activity]
PPAR agonist. Antihyperlipoproteinemic. | [storage]
Store at -20°C |
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