| Identification | More | [Name]
2-Hydroxy-5-methyl-3-nitropyridine | [CAS]
7464-14-4 | [Synonyms]
2-HYDROXY-3-NITRO-5-METHYLPYRIDINE
2-HYDROXY-3-NITRO-5-PICOLINE
2-HYDROXY-5-METHYL-3-NITROPYRIDINE
3-(NITRO)-5-METHYLPYRIDIN-2-OL
5-METHYL-3-NITRO-2(1H)-PYRIDINONE
2-Hydroxy-5-methyl-3-nitropyridine 98%
5-Methyl-3-nitropyridin-2-ol
2-HYDROXY-3-NITRO-5-PICOLINE (2-HYDROXY-5-METHYL-3-NITROPYRIDINE) | [Molecular Formula]
C6H6N2O3 | [MDL Number]
MFCD02070021 | [Molecular Weight]
154.12 | [MOL File]
7464-14-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
179 °C (dec.) (lit.) | [Boiling point ]
353.3±35.0 °C(Predicted) | [density ]
1.24 g/mL at 25 °C(lit.) | [Fp ]
179 °C | [storage temp. ]
2-8°C | [solubility ]
soluble in Dimethylformamide | [form ]
powder to crystal | [pka]
8.78±0.10(Predicted) | [color ]
White to Yellow | [CAS DataBase Reference]
7464-14-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
2933399990 |
| Hazard Information | Back Directory | [Description]
2-Hydroxy-5-methyl-3-nitropyridine (HMPN) is an organosynthetic compound that can be used as a feedstock for the synthesis of other compounds or as a biological inhibitor, such as in the preparation of 2-chloro-5-methyl-3-nitropyridine and transglutaminase 2 (tg2) inhibitors. It reacts with molybdenum and chloride. It is able to react with molybdenum and chloride, and it is able to increase the reaction yield and time. It is also used to explain its reactivity with xylene. | [Chemical Properties]
Powder or crystalline | [Uses]
2-Hydroxy-5-methyl-3-nitropyridine may be used in the preparation of 2-chloro-5-methyl-3-nitropyridine via chlorination, using thionyl chloride. It may also be used is preparing proteasome inhibitors containing 5-methylpyridin-2(1H)-one moiety. |
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