Identification | More | [Name]
D(+)-Malic acid | [CAS]
636-61-3 | [Synonyms]
D-(+)-APPLE ACID D-APPLE ACID D-HYDROXYBUTANEDIOIC ACID D-HYDROXYSUCCINIC ACID (+)-D-MALIC ACID D-(+)-MALIC ACID D-MALIC ACID MALIC ACID, D-(+)- (R)-2-HYDROXYBUTANEDICARBOXYLIC ACID (R)-2-HYDROXY-SUCCINIC ACID R(+)-2-HYDROXYSUCCINIC ACID (r)-hydroxybutanedioic acid (R)-(+)-HYDROXYSUCCINIC ACID (R)-HYDROXYSUCCINIC ACID (R)-(+)-MALIC ACID (R)-MALIC ACID Butanedioic acid, hydroxy-, (R)- hydroxy-,(R)-Butanedioicacid l(+)-malicaci D-MALIC ACID 100MG NEAT | [EINECS(EC#)]
211-262-2 | [Molecular Formula]
C4H6O5 | [MDL Number]
MFCD00004245 | [Molecular Weight]
134.09 | [MOL File]
636-61-3.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
98-102 °C (lit.) | [alpha ]
2.2 º (c=3, H2O) | [Boiling point ]
167.16°C (rough estimate) | [density ]
1.60 | [refractive index ]
6.5 ° (C=10, Acetone) | [storage temp. ]
Store below +30°C. | [solubility ]
Soluble in methanol, ethanol, acetone, ether. | [form ]
Crystalline Powder | [pka]
3.61±0.23(Predicted) | [color ]
White | [PH]
2.2 (10g/l, H2O, 20℃) | [optical activity]
[α]20/D +28.0±2°, c = 5.5% in pyridine | [Water Solubility ]
soluble | [Detection Methods]
T,NMR,M.P | [Merck ]
14,5707 | [BRN ]
1723540 | [LogP]
-1.370 (est) | [CAS DataBase Reference]
636-61-3(CAS DataBase Reference) | [NIST Chemistry Reference]
(r)-Hydroxybutanedioic acid(636-61-3) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R37/38:Irritating to respiratory system and skin . R41:Risk of serious damage to eyes. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
ON7260000
| [HS Code ]
29181980 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece | [Definition]
ChEBI: An optically active form of malic acid having (R)-configuration. | [Biological Activity]
D-(+)-Malic acid, an active isomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport. | [Synthesis]
Malic acid is isolated from immature apples; industrially prepared is obtained by catalytic oxidation of benzene, then reacting with water at high temperature and high pressure to generate maleic anhydride. | [in vitro]
Some bacteria belonging to Arthrobacter, Brevibacterium, Corynebacterium, Pseudomonas, Bacillus, and Acinetobacter produced D-(+)-Malic acid (D-Malic acid) from Maleic acid when the cells grown in a medium containing citraconic acid are reacted aerobically with Maleic acid in the pH 7.0 phosphate buffer containing 0.1% sodium chloride. |
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