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ChemicalBook--->CAS DataBase List--->627-03-2

627-03-2

627-03-2 Structure

627-03-2 Structure
IdentificationMore
[Name]

Ethoxyacetic acid
[CAS]

627-03-2
[Synonyms]

ETHOXYACETIC ACID
GLYCOLIC ACID ETHYL ETHER
O-ETHYLGLYCOLIC ACID
2-Ethoxyacetic acid
2-ethoxyaceticacid
Aceticacid,ethoxy-
ethoxy-aceticaci
Ethoxyethanoicacid
Ethylglycolicacid
Glycollicacidethylether
α-Ethylglycollicacid
Ethoxyaceticacid,97%
Ethoxyacetic
ethyloglycolic acid
Ethyloxyacetic acid
Glycolic ethyl ether
[EINECS(EC#)]

210-978-2
[Molecular Formula]

C4H8O3
[MDL Number]

MFCD00004310
[Molecular Weight]

104.1
[MOL File]

627-03-2.mol
Chemical PropertiesBack Directory
[Appearance]

liquid
[Boiling point ]

97-100 °C/11 mmHg (lit.)
[density ]

1.102 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.419(lit.)
[Fp ]

208 °F
[storage temp. ]

Sealed in dry,2-8°C
[form ]

Liquid
[pka]

3.65(at 18℃)
[color ]

Clear colorless to light yellow
[Stability:]

Stable. Combustible. Incompatible with strong oxidizing agents.
[Water Solubility ]

soluble
[BRN ]

1743037
[CAS DataBase Reference]

627-03-2(CAS DataBase Reference)
[NIST Chemistry Reference]

Acetic acid, ethoxy-(627-03-2)
[EPA Substance Registry System]

627-03-2(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

C,Xi
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN 3265 8/PG 2
[WGK Germany ]

3
[RTECS ]

AH3600000
[Hazard Note ]

Irritant
[TSCA ]

Yes
[HazardClass ]

8
[PackingGroup ]

III
[HS Code ]

29189900
[Safety Profile]

Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium ethylate solution,in ethyl alcohol-->ETHOXYACETALDEHYDE-->Magnesium, chloro(ethoxymethyl)--->NISTC51770980-->2-ethoxyacetonitrile-->Sodium ethoxide-->2-Ethoxyethanol-->Ethanol-->Carbon dioxide-->Bromoacetic acid-->Chloromethyl ethyl ether-->Sodium chloroacetate
[Preparation Products]

Ethyl ethoxyacetate-->Cetirizine-->ETHYL 2-ETHOXY-2-HYDROXYACETATE-->Diethyl ether
Hazard InformationBack Directory
[General Description]

Liquid.
[Reactivity Profile]

An ether and organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat.
[Air & Water Reactions]

Water soluble.
[Health Hazard]

ACUTE/CHRONIC HAZARDS: This compound is corrosive.
[Fire Hazard]

This chemical is combustible.
[Chemical Properties]

liquid
[Uses]

Ethoxyacetic acid is used to evaluate toxicity in embryonic stem cell test in mice. It finds application as a biomarker of exposure to alkyl-substituted ethylene glycols and other aliphatic ethers. It is used as a precursor to prepare ethoxy-acetic acid ethoxymethyl ester.
[Definition]

ChEBI: Ethoxyacetic acid is a carboxylic acid.
[Biochem/physiol Actions]

Ethoxyacetic acid induces testicular toxicity in rats in vivo .
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

O-Ethylglycolic acid(627-03-2).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Ethoxyacetic acid(627-03-2)MS
Ethoxyacetic acid(627-03-2)1HNMR
Ethoxyacetic acid(627-03-2)13CNMR
Ethoxyacetic acid(627-03-2)IR1
Ethoxyacetic acid(627-03-2)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Ethoxyacetic acid, 98%(627-03-2)
[Alfa Aesar]

Ethoxyacetic acid, 98%(627-03-2)
[Sigma Aldrich]

627-03-2(sigmaaldrich)
[TCI AMERICA]

Ethoxyacetic Acid,>98.0%(GC)(T)(627-03-2)
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