| Identification | More | [Name]
Cinnamamide | [CAS]
621-79-4 | [Synonyms]
3-PHENYLACRYLAMIDE
CINNAMAMIDE
TIMTEC-BB SBB004096
TRANS-3-PHENYLACRYLAMIDE
TRANS-CINNAMAMIDE
(2E)-3-Phenyl-2-propenamide
2-Benzylideneacetamide
2-Propenamide, 3-phenyl-
3-phenyl-2-propenamid
3-phenyl-2-propenamide
3-Phenylpropenamide
Cinnamic amide
Cinnamide
Cinnamylamide
ginnamicacidamide
Cinnamamide,predominantly trans
Cinnamanmide
CINNAMAMIDE, 97%, PREDOMINANTLY TRANS
Cinnamamide, 97+%
Benzeneacrylamide | [EINECS(EC#)]
210-707-8 | [Molecular Formula]
C9H9NO | [MDL Number]
MFCD00008033 | [Molecular Weight]
147.17 | [MOL File]
621-79-4.mol |
| Chemical Properties | Back Directory | [Appearance]
OFF-WHITE TO BEIGE CRYSTALLINE POWDER | [Melting point ]
148-150 °C(lit.)
| [Boiling point ]
267.28°C (rough estimate) | [density ]
1.1135 (rough estimate) | [refractive index ]
1.5450 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
15?+-.0.50(Predicted) | [color ]
Off-white to beige | [BRN ]
2040577 | [InChIKey]
APEJMQOBVMLION-VOTSOKGWSA-N | [Uses]
Cinnamamide, a non-lethal repellent, deters feeding by a wide range of avian species. | [CAS DataBase Reference]
621-79-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzylidene acetamide(621-79-4) | [EPA Substance Registry System]
621-79-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
GD6853000
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29242990 |
| Hazard Information | Back Directory | [Chemical Properties]
OFF-WHITE TO BEIGE CRYSTALLINE POWDER | [Definition]
ChEBI: The simplest member of the class of cinnamamides that consists of acrylamide bearing a phenyl substituent at the 3-position. | [Biological Activity]
Cinnamamide is an amide form of of trans-cinnamic acid and a metabolite of Streptomyces. Cinnamamide exhibits low cytotoxicity against BEL-7402 human hepatoma cells and HT-1080 fibrosarcoma cells and inhibits cell growth (IC50s = 1.94 and 1.29 mM, respectively). In vivo, cinnamamide (40 and 100 mg/kg, i.p.) reduces tumor weight in a mouse model of C26 murine colon carcinoma. Cinnamamide (75 and 150 mg/kg, i.p.) also reduces tumor weight in a mouse model of murine hepatoma 22 by 42% and 49%, respectively, without reducing body weight when delivered one or three days following tumor implantation. When presented with cinnamamide-treated food at a concentration of 0.8% w/w, house and wood mice food consumption is reduced to 32% and 17% of pretreatment levels, respectively, however, wood mouse consumption returns to pretrial levels by day two. | [storage]
Store at -20°C |
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