| Identification | Back Directory | [Name]
hydroxygenkwanin | [CAS]
20243-59-8 | [Synonyms]
Hydroxygenwanin
hydroxygenkwanin
7-O-Methylluteolin
hydroxyl genkwanin
3'-hydroxygenkwanin
Hydroxygenkwanin ,98%
Luteolin 7-methylether
2-(3,4-Dihydroxyphenyl)
hydroxygenkwanin USP/EP/BP
3',4',5-Trihydroxy-7-methoxyflavone
5,3',4'-Trihydroxy-7-methoxyflavone
-5-hydroxy-7-methoxy-4H-chromen-4-one
3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
2-(3,4-Dihydroxyphenyl)-7-methoxy-5-hydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy- | [Molecular Formula]
C16H12O6 | [MDL Number]
MFCD11046350 | [MOL File]
20243-59-8.mol | [Molecular Weight]
300.26 |
| Chemical Properties | Back Directory | [Melting point ]
258-260 °C | [Boiling point ]
602.7±55.0 °C(Predicted) | [density ]
1.512±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 1 mg/ml; DMSO: 2 mg/ml | [form ]
A solid | [pka]
6.33±0.40(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from coriander flower. | [Uses]
Hydroxyflorin has antitussive, expectorant and asthmatic effects. | [Definition]
ChEBI: Luteolin 7-methyl ether is a member of flavonoids and an ether. It is a conjugate acid of a luteolin-5-olate 7-methyl ether. | [Biological Activity]
Hydroxygenkwanin (7-O-Methylluteolin) is a natural flavonoid that is one of the main components of Clove Daphne. It has antioxidant, antiglioma and anticancer effects. | [in vitro]
Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner.
It induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway. |
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