| Identification | Back Directory | [Name]
C.I. 75710 | [CAS]
491-50-9 | [Synonyms]
C.I. 75710
QuerciMeritroside
Quercetin 7-glucoside
quercetin7-O-β-D-glucoside
quercetin 7-O-β-D-glucoside
quercetin 7-O-beta-D-glucoside
Quercetin-7-O-β-D-glucopyranosid
Quercetin-7-O-b-D-glucopyranoside
Quercetin-7-O-2-D-glucopyranoside
Quercetin-7-O-β-D-glucopyranoside
Quercetin-7-O-beta-D-glucopyranoside
7-(β-D-Glucopyranosyloxy)-5,3',4'-trihydroxyflavonol
7-(β-D-Glucopyranosyloxy)-3,3',4',5-tetrahydroxyflavone
7-(β-D-Glucopyranosyloxy)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-3,5-dihydroxy-
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-3,5-dihydroxy- | [Molecular Formula]
C21H20O12 | [MDL Number]
MFCD01762823 | [MOL File]
491-50-9.mol | [Molecular Weight]
464.38 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 0.3 mg/ml | [Boiling point ]
859.2±65.0 °C(Predicted) | [density ]
1.809±0.06 g/cm3(Predicted) | [form ]
A crystalline solid | [Melting point ]
248 °C | [pka]
5.92±0.40(Predicted) | [color ]
White to yellow | [LogP]
-0.367 (est) |
| Hazard Information | Back Directory | [Occurrence]
Quercimeritrin is a natural product found in Dendroviguiera sphaerocephala, Dendroviguiera eriophora, and other organisms with data available. | [Definition]
ChEBI: A quercetin O-glucoside in which a glucosyl residue is attached at position 7 of quercetin via a beta-glycosidic linkage. | [Antimicrobial activity]
Quercetin-7-O-beta-D-glucopyranoside has antibacterial activity, it shows promising activity against Staphylococcus aureus. Quercetin 7-O-beta-D-glucopyranoside exhibits strong antioxidative, and anti-inflammatory activities, inhibiting expression of inducible nitric oxide synthase and release of nitric oxide by lipopolysaccharide-stimulated RAW 264.7 macrophages in a dose-dependent manner. It inhibits overexpression of cyclooxygenase-2 and granulocyte macrophage-colony-stimulating factor. | [Biological Activity]
Quercetin-7-O-β-D-glucopyranoside is a flavonoid originally isolated from G. hirsutum that has diverse biological activities, including antioxidant, anti-inflammatory, and anti-angiogenic properties. It has antioxidant activity in a oxygen radical absorbance capacity (ORAC) assay and decreases tert-butyl hydroperoxide-induced reactive oxygen species (ROS) production in L-929 cells when used at concentrations of 0.25 and 1 μg/ml. Quercetin-7-O-β-D-glucopyranoside (15 and 30 μg/ml) reduces protein levels of inducible nitric oxide synthase (iNOS) and COX-2 in LPS-stimulated RAW 264.7 cells. It decreases angiogenesis in isolated rat aortic rings and proliferation of human umbilical vein endothelial cells (HUVECs) but has no effect on tube formation or chemotaxis of HUVECs when used at a concentration of 100 μM. |
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