Identification | Back Directory | [Name]
Mal-PEG2-NHS ester | [CAS]
1433997-01-3 | [Synonyms]
Mal-PEG2-NHS ester 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C15H18N2O8 | [MDL Number]
MFCD24539465 | [MOL File]
1433997-01-3.mol | [Molecular Weight]
354.31 |
Hazard Information | Back Directory | [Description]
Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | [Uses]
Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers. |
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