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ChemicalBook--->CAS DataBase List--->756525-99-2

756525-99-2

756525-99-2 Structure

756525-99-2 Structure
IdentificationBack Directory
[Name]

alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)
[CAS]

756525-99-2
[Synonyms]

N-Succinim
Mal-PEG4-NHS
Mal-NH-PEG4-NHS
Mal-amido-PEG4-NHS
MAL-DPEG4-NHS Ester
Mal-NH-PEG4-NHS ester
MAL-NH-PEG4-CH2CH2COONHS
Maleimide-PEG4-NHS Ester
Maleimide-PEG4-succinimidyl Ester
Maleimide-NH-PEG4-CH2CH2COONHS Ester
Maleimidopropionyl-PEG4-CH2CH2COONHS Ester
alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)
3-(2-Maleimidoethylcarbamoyl)-peg4-propionic acid N-hydroxysuccinimide ester
O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol
O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol >=90% (NMR)
2,5-dioxopyrrolidin-1-yl 19-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-oate
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate
N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
[EINECS(EC#)]

201-258-5
[Molecular Formula]

C22H31N3O11
[MDL Number]

MFCD11041113
[MOL File]

756525-99-2.mol
[Molecular Weight]

513.49
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

15.01±0.46(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319
[Precautionary statements ]

P261-P305+P351+P338
[WGK Germany ]

3
[HS Code ]

2928009090
Hazard InformationBack Directory
[Description]

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

Maleimide-PEG4-NHS (CAS# 756525-99-2) is a cross-linking compound used in the lysosomal acid-triggered release of anticancer drugs.
[reaction suitability]

reagent type: cross-linking reagent
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