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ChemicalBook--->CAS DataBase List--->1252257-56-9

1252257-56-9

1252257-56-9 Structure

1252257-56-9 Structure
IdentificationBack Directory
[Name]

SPDP-PEG8-NHS ester
[CAS]

1252257-56-9
[Synonyms]

LC-PEG8-SPDP
SDPD-PEG8-NHS
Opss-peg(8)-nhs
SPDP-PEG8-NHS ester
SPDP-dPEG(R)8-NHS ester
Propanoic acid, 3-[[25-oxo-27-(2-pyridinyldithio)-3,6,9,12,15,18,21-heptaoxa-24-azaheptacos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C31H49N3O13S2
[MDL Number]

MFCD13185003
[MOL File]

1252257-56-9.mol
[Molecular Weight]

735.86
Chemical PropertiesBack Directory
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

solid or viscous liquid
[pka]

15.01±0.46(Predicted)
Hazard InformationBack Directory
[Description]

SPDP-PEG8-NHS ester is a PEG linker containing an SPDP crosslinker and an NHS ester. The SPDP crosslinker is reactive toward amine and thiol groups and contains a cleavable disulfide bond. This crosslinker is also membrane permeable which allows for intracellular reactions to take place. The NHS ester can react with primary amines to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
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