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ChemicalBook CAS DataBase List Sparfloxacin
110871-86-8

Sparfloxacin synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 94 percent / acetic acid, aq. H2SO4 / 0.17 h / 100 °C
2: 63 percent / pyridine / 0.67 h / 80 °C

References:

Miyamoto, Teruyuki;Matsumoto, Jun-ichi;Chiba, Katsumi;Egawa, Hiroshi;Shibamori, Koh-ichiro;et al. [Journal of Medicinal Chemistry,1990,vol. 33,# 6,p. 1645 - 1656]

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107564-02-3 Synthesis
3-Quinolinecarboxylic acid, 1-cyclopropyl-5,6,7,8-tetrafluoro-1,4-dihydro-4-oxo-, ethyl ester

107564-02-3
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