Enrofloxacin synthesis
- Product Name:Enrofloxacin
- CAS Number:93106-60-6
- Molecular formula:C19H22FN3O3
- Molecular Weight:359.39
5308-25-8
452 suppliers
$15.00/5G
86393-33-1
341 suppliers
$15.00/25g
93106-60-6
624 suppliers
$6.00/1g
Yield:93106-60-6 97%
Reaction Conditions:
with nano iron oxide on ZrO2 coated sulfonic acid in water; for 0.316667 h;Reflux;Solvent;Temperature;Reagent/catalyst;
Steps:
3.2. General Experimental Procedure
A mixture of 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 1a (1 mmol) and Nethylpiperazine2y (1.5 mmol) and n-FZSA (0.06 g) as catalystin H2O (5 ml) were heated under reflux for the appropriatetime. The reaction was monitored by TLC. After appropriatetime, the catalyst was separated using an externalmagnet and washed with hot ethanol (5 mL). The reactionmixture was then cooled to room temperature. The precipitatedsolid was collected by filtration, and recrystallized fromethanol 96% to give desired compound in high yields.
References:
Nakhaei, Ahmad;Ramezani, Shirin;Shams-Najafi, Sayyed Jalal;Farsinejad, Sadaf [Letters in Organic Chemistry,2018,vol. 15,# 9,p. 739 - 746]
![Propanedioic acid, 2-[[cyclopropyl[3-(4-ethyl-1-piperazinyl)phenyl]amino]methylene]-, 1,3-bis(trimethylsilyl) ester](/CAS/20210305/GIF/131776-44-8.gif)
131776-44-8
0 suppliers
inquiry
93106-60-6
624 suppliers
$6.00/1g
86393-34-2
180 suppliers
$7.00/5g
93106-60-6
624 suppliers
$6.00/1g