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ChemicalBook CAS DataBase List Diethylamine hydrochloride
660-68-4

Diethylamine hydrochloride synthesis

3synthesis methods
-

Yield:660-68-4 100%

Reaction Conditions:

with hydroxylamine hydrochloride in ethanol for 2 h;Reflux;

Steps:

General procedure for the preparation of amine hydrochloride salts 2c-2r
General procedure: To a 25-mL round-bottomed flask containing ammonium chloride (0.54 g, 10 mmol) was added ethanol (3 mL) followed by the requisite amine (10 mmol). The mixture was magnetically stirred and refluxed for 2 h. The solvent was then removed by rotary evaporation affording the hydrochloride salt as a solid invariably in quantitative yield.

References:

Di Grandi, Martin J.;Bennett, Caitlin;Cagino, Kristen;Muccini, Arnold;Suraci, Corey;Saba, Shahrokh [Synthetic Communications,2015,vol. 45,# 22,p. 2601 - 2607] Location in patent:supporting information

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