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ChemicalBook CAS DataBase List Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate
84501-68-8

Ethyl 4-[[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]piperidine-1-carboxylate synthesis

12synthesis methods
58859-46-4 Synthesis
Ethyl 4-amino-1-piperidinecarboxylate

58859-46-4
219 suppliers
$13.00/5g

84946-20-3 Synthesis
1-(4-Fluorobenzyl)-2-chlorobenzimidazole

84946-20-3
232 suppliers
$8.00/1g

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Yield:84501-68-8 98%

Reaction Conditions:

in neat (no solvent) at 170; for 4 h;

References:

Kumar, Malkeet;Okombo, John;Mambwe, Dickson;Taylor, Dale;Lawrence, Nina;Reader, Janette;Van Der Watt, Mari?tte;Fontinha, Diana;Sanches-Vaz, Margarida;Bezuidenhout, Belinda C.;Lauterbach, Sonja B.;Liebenberg, Dale;Birkholtz, Lyn-Marie;Coetzer, Theresa L.;Prudêncio, Miguel;Egan, Timothy J.;Wittlin, Sergio;Chibale, Kelly [ACS Infectious Diseases,2019,vol. 5,# 2,p. 303 - 315]

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