6-BROMO-2-CHLOROQUINOLINE-4-CARBONYL CHLORIDE synthesis
- Product Name:6-BROMO-2-CHLOROQUINOLINE-4-CARBONYL CHLORIDE
- CAS Number:287176-63-0
- Molecular formula:C10H4BrCl2NO
- Molecular Weight:304.95
5463-29-6
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$55.00/250mg
287176-63-0
22 suppliers
$335.00/10g
Yield:-
Steps:
Multi-step reaction with 2 steps
1: trichlorophosphate / 2 h / Reflux
2: thionyl chloride / 3 h / Reflux; Inert atmosphere
References:
Cappelli, Andrea;Anzini, Maurizio;Castriconi, Federica;Grisci, Giorgio;Paolino, Marco;Braile, Carlo;Valenti, Salvatore;Giuliani, Germano;Vomero, Salvatore;Di Capua, Angela;Betti, Laura;Giannaccini, Gino;Lucacchini, Antonio;Ghelardini, Carla;Di Cesare Mannelli, Lorenzo;Frosini, Maria;Ricci, Lorenzo;Giorgi, Gianluca;Mascia, Maria Paola;Biggio, Giovanni [Journal of Medicinal Chemistry,2016,vol. 59,# 7,p. 3353 - 3372]