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ChemicalBook CAS DataBase List 4-Hydroxybenzyl cyanide
14191-95-8

4-Hydroxybenzyl cyanide synthesis

14synthesis methods
-

Yield:14191-95-8 94%

Reaction Conditions:

in ethanol

Steps:

2 Preparation of para-hydroxybenzyl cyanide
EXAMPLE 2 Preparation of para-hydroxybenzyl cyanide A mixture of 4.96 g. para-hydroxybenzyl alcohol 2.4 g. sodium cyanide 12 ml. ethanol and 12 ml. ethyl formate is heated with stirring under reflux for a period of ninety minutes. The reaction product is then subjected to the same isolation process as in Example 1 to give a 94% yield of crude product showing a melting point of 58°-61° C. uncorrected.

References:

A. H. Marks & Co., Limited US4378319, 1983, A

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