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ChemicalBook CAS DataBase List 3-Pyridylacetic acid
501-81-5

3-Pyridylacetic acid synthesis

10synthesis methods
-

Yield:501-81-5 100%

Reaction Conditions:

with potassium hydroxide in ethanol

Steps:

3.1
(1) To a suspension of 2-(pyridin-3-yl)acetic acid-hydrochloride (13.2g, 75.6mmol) in ethanol (100mL) was added a solution (150mL) of 0.5mol potassium hydroxide/ethanol, and the mixture was stirred well, then filtered to remove potassium chloride, concentrated, and dried to give 2-(pyridin-3-yl)acetic acid (10.6g, quantitative).

References:

Grelan Pharmaceutical Co., Ltd. EP1559716, 2005, A1 Location in patent:Page/Page column 20

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