VS-5584
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- $32 - $2395.3
- Product name: VS-5584
- CAS: 1246560-33-7
- MF: C17H22N8O
- MW: 354.41
- EINECS:
- MDL Number:MFCD25372027
- Synonyms:2-Pyrimidinamine, 5-[8-methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-;5-[8-Methyl-9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine VS-5584;VS-5584, >=98%;VS-5584;SB 2343;SB2343;5-(9-Isopropyl-8-Methyl-2-Morpholin-4-yl-9H-purin-6-yl)-pyriMidin-2-ylaMine;5-(9-ISOPROPYL-8-METHYL-2-MORPHOLINO-9H-PURIN-6-YL)PYRIMIDIN-2-AMINE
20 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product number2797AH
- Product description5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
- Packaging10mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2797AH
- Product description5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3927
- Product descriptionVS-5584(SB2343)
- Packaging50mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180870
- Product descriptionVS-5584 >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180870
- Product descriptionVS-5584 >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180870
- Product descriptionVS-5584 >98%
- Packaging1000mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16294
- Product descriptionVS-5584 ≥98%
- Packaging10mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16294
- Product descriptionVS-5584 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16294
- Product descriptionVS-5584 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM138601
- Product description5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine 98%
- Packaging50mg
- Price$324
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1202
- Product descriptionVS-5584 98.15%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1202
- Product descriptionVS-5584 98.15%
- Packaging50mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1202
- Product descriptionVS-5584 98.15%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1202
- Product descriptionVS-5584 98.15%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004110
- Product descriptionVS-5584 98+%
- Packaging50mg
- Price$346
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004110
- Product descriptionVS-5584 98+%
- Packaging10mg
- Price$102
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2797AH | 5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine | 10mg | $353 | 2021-12-16 | Buy |
| AK Scientific | 2797AH | 5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine | 1mg | $133 | 2021-12-16 | Buy |
| ApexBio Technology | A3927 | VS-5584(SB2343) | 50mg | $400 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180870 | VS-5584 >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180870 | VS-5584 >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180870 | VS-5584 >98% | 1000mg | $2395.3 | 2021-12-16 | Buy |
| Cayman Chemical | 16294 | VS-5584 ≥98% | 10mg | $230 | 2024-03-01 | Buy |
| Cayman Chemical | 16294 | VS-5584 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 16294 | VS-5584 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Chemenu | CM138601 | 5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine 98% | 50mg | $324 | 2021-12-16 | Buy |
| ChemScene | CS-1202 | VS-5584 98.15% | 100mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-1202 | VS-5584 98.15% | 50mg | $400 | 2021-12-16 | Buy |
| ChemScene | CS-1202 | VS-5584 98.15% | 10mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-1202 | VS-5584 98.15% | 5mg | $90 | 2021-12-16 | Buy |
| Crysdot | CD31004110 | VS-5584 98+% | 50mg | $346 | 2021-12-16 | Buy |
| Crysdot | CD31004110 | VS-5584 98+% | 10mg | $102 | 2021-12-16 | Buy |
Properties
Boiling point :687.2±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥17.7 mg/mL in DMSO; ≥4.71 mg/mL in EtOH with ultrasonic
form :solid
pka :4.53±0.10(Predicted)
color :Light yellow to yellow
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥17.7 mg/mL in DMSO; ≥4.71 mg/mL in EtOH with ultrasonic
form :solid
pka :4.53±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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Description
Phosphatidylinositol 3-kinase (PI3K) signaling through Akt/PKB and the mammalian target of rapamycin (mTOR) controls gene expression related to cell proliferation, differentiation, and apoptosis. Increased activity of this pathway is important in many types of cancer. VS-5584 is a purine analog that inhibits mTOR (IC50 = 37 nM) and PI3K (IC50s = 16, 68, 25, and 42 nM for the α, β, γ, and δ isoforms, respectively) without relevant activity against more than 400 additional lipid and protein kinases. By inhibiting the phosphorylation of substrates downstream of PI3K and mTOR, VS-5584 demonstrates broad anti-proliferative sensitivity leading to tumor growth inhibition in human tumor models.More related product prices
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