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ChemicalBook >> CAS DataBase List >> IPI 145

IPI 145

IPI 145 price.
  • $68 - $2550
  • Product name: IPI 145
  • CAS: 1201438-56-3
  • MF: C22H17ClN6O
  • MW: 416.86
  • EINECS:200-256-5
  • MDL Number:MFCD15144635
  • Synonyms:IPI-145;IPI-145 (INK-1197);IPI-145 INK197;8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone;IPI-145, >=98%;Duvelisib (IPI-145, INK1197);DUVELISIB (IPI-145);1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-
29 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1175-M005
  • Product descriptionIPI-145 ≥95%
  • Packaging5mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1175-M050
  • Product descriptionIPI-145 ≥95%
  • Packaging50mg
  • Price$1004
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1175
  • Product descriptionIPI145
  • Packaging100mg
  • Price$1660
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60268
  • Product descriptionDuvelisib(IPI-145)
  • Packaging20mg
  • Price$258
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146252
  • Product descriptionDuvelisib (IPI-145, INK1197) >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146252
  • Product descriptionDuvelisib (IPI-145, INK1197) >98%
  • Packaging250mg
  • Price$1060.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146252
  • Product descriptionDuvelisib (IPI-145, INK1197) >98%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP43074
  • Product descriptionIPI 145
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP43074
  • Product descriptionIPI 145
  • Packaging50mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16800
  • Product descriptionIPI-145 ≥98%
  • Packaging500μg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16800
  • Product descriptionIPI-145 ≥98%
  • Packaging1mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16800
  • Product descriptionIPI-145 ≥98%
  • Packaging5mg
  • Price$201
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16800
  • Product descriptionIPI-145 ≥98%
  • Packaging10mg
  • Price$335
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM138713
  • Product description(S)-3-(1-(9H-Purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one 98%
  • Packaging100mg
  • Price$299
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0888
  • Product descriptionDuvelisib 99.91%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0888
  • Product descriptionDuvelisib 99.91%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1175-M005 IPI-145 ≥95% 5mg $178 2021-12-16 Buy
Adipogen Life Sciences SYN-1175-M050 IPI-145 ≥95% 50mg $1004 2021-12-16 Buy
AK Scientific SYN1175 IPI145 100mg $1660 2021-12-16 Buy
Arctom CFN60268 Duvelisib(IPI-145) 20mg $258 2021-12-16 Buy
Biorbyt Ltd orb146252 Duvelisib (IPI-145, INK1197) >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146252 Duvelisib (IPI-145, INK1197) >98% 250mg $1060.8 2021-12-16 Buy
Biorbyt Ltd orb146252 Duvelisib (IPI-145, INK1197) >98% 1g $2245.7 2021-12-16 Buy
Biosynth Carbosynth FP43074 IPI 145 10mg $125 2021-12-16 Buy
Biosynth Carbosynth FP43074 IPI 145 50mg $225 2021-12-16 Buy
Cayman Chemical 16800 IPI-145 ≥98% 500μg $68 2024-03-01 Buy
Cayman Chemical 16800 IPI-145 ≥98% 1mg $121 2024-03-01 Buy
Cayman Chemical 16800 IPI-145 ≥98% 5mg $201 2024-03-01 Buy
Cayman Chemical 16800 IPI-145 ≥98% 10mg $335 2024-03-01 Buy
Chemenu CM138713 (S)-3-(1-(9H-Purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one 98% 100mg $299 2021-12-16 Buy
ChemScene CS-0888 Duvelisib 99.91% 5mg $70 2021-12-16 Buy
ChemScene CS-0888 Duvelisib 99.91% 10mg $100 2021-12-16 Buy

Properties

Melting point :205-206o C
Boiling point :757.8±60.0 °C(Predicted)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White solid.
pka :10.05±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:

Description

IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kγ and PI3Kδ (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kγ and PI3Kδ are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus animal models. It also has potential applications in immunotherapy and in certain cancers.

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