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ChemicalBook >> CAS DataBase List >> TPEN

TPEN

TPEN price.
  • $17 - $1683
  • Product name: TPEN
  • CAS: 16858-02-9
  • MF: C26H28N6
  • MW: 424.54
  • EINECS:
  • MDL Number:MFCD00036918
  • Synonyms:N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE;TETRAKIS-(2-PYRIDYLMETHYL)ETHYLENEDIAMINE;N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-Ethanediamine;TPEN;1,2-Ethanediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-;1,2-Ethanediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)-, (oc-6-11)-;N1,N1,N2,N2-tetrakis(pyridin-2-ylMethyl)ethane-1,2-diaMine;N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
42 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 25mg
  • 500mg
  • 1g
  • 2.5G
  • 100
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 300mg
  • 5g
  • ManufacturerAK Scientific
  • Product number8604AA
  • Product descriptionN1,N1,N2,N2-Tetrakis(pyridin-2-ylmethyl)ethane-1,2-diamine
  • Packaging5g
  • Price$1093
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64206
  • Product descriptionN,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine
  • Packaging100mg
  • Price$136
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64206
  • Product descriptionN,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine
  • Packaging300mg
  • Price$262.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA539105
  • Product descriptionTPEN 95+%
  • Packaging50mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA539105
  • Product descriptionTPEN 95+%
  • Packaging100mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA539105
  • Product descriptionTPEN 95+%
  • Packaging250mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA539105
  • Product descriptionTPEN 95+%
  • Packaging1g
  • Price$251
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA539105
  • Product descriptionTPEN 95+%
  • Packaging5g
  • Price$866
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0014631
  • Product descriptionN,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)-1,2-ETHYLENEDIAMINE 95.00%
  • Packaging250MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0014631
  • Product descriptionN,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)-1,2-ETHYLENEDIAMINE 95.00%
  • Packaging2.5G
  • Price$1683
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7642
  • Product descriptionTPEN
  • Packaging100mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS246576
  • Product descriptionTPEN ≥95%
  • Packaging50mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS246576
  • Product descriptionTPEN ≥95%
  • Packaging100mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS246576
  • Product descriptionTPEN ≥95%
  • Packaging250mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS246576
  • Product descriptionTPEN ≥95%
  • Packaging1g
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS246576
  • Product descriptionTPEN ≥95%
  • Packaging5g
  • Price$857
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8604AA N1,N1,N2,N2-Tetrakis(pyridin-2-ylmethyl)ethane-1,2-diamine 5g $1093 2021-12-16 Buy
Alfa Aesar J64206 N,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine 100mg $136 2024-03-01 Buy
Alfa Aesar J64206 N,N,N',N'-Tetrakis-(2-pyridylmethyl)ethylenediamine 300mg $262.65 2024-03-01 Buy
Ambeed A539105 TPEN 95+% 50mg $38 2021-12-16 Buy
Ambeed A539105 TPEN 95+% 100mg $67 2021-12-16 Buy
Ambeed A539105 TPEN 95+% 250mg $86 2021-12-16 Buy
Ambeed A539105 TPEN 95+% 1g $251 2021-12-16 Buy
Ambeed A539105 TPEN 95+% 5g $866 2021-12-16 Buy
American Custom Chemicals Corporation CHM0014631 N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)-1,2-ETHYLENEDIAMINE 95.00% 250MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation CHM0014631 N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)-1,2-ETHYLENEDIAMINE 95.00% 2.5G $1683 2021-12-16 Buy
ApexBio Technology B7642 TPEN 100mg $108 2021-12-16 Buy
Arctom AS246576 TPEN ≥95% 50mg $38 2021-12-16 Buy
Arctom AS246576 TPEN ≥95% 100mg $66 2021-12-16 Buy
Arctom AS246576 TPEN ≥95% 250mg $85 2021-12-16 Buy
Arctom AS246576 TPEN ≥95% 1g $248 2021-12-16 Buy
Arctom AS246576 TPEN ≥95% 5g $857 2021-12-16 Buy

Properties

Melting point :110-112 °C
Boiling point :530.56°C (rough estimate)
Density :1.3893 (rough estimate)
refractive index :1.4570 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml).
pka :5.19±0.12(Predicted)
form :Tan solid
color :Off-white or tan
BRN :4211982
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :16858-02-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

As a cofactor of more than 300 enzymes, zinc is integral for a wide variety of cellular processes that affect most biological functions. Most notably, its bioavailability is important to the regulation of apoptosis, cell proliferation, and differentiation. TPEN is a cell permeant metal ion chelator that is used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral. At a concentration as low as 6 μM, TPEN-induced zinc depletion decreases X-linked inhibitor of apoptosis (XIAP) levels in human PC-3 prostate cancer cells and promotes caspase-3 and -9 activation. At 25 μM, TPEN attenuates hypoxic pulmonary vasoconstriction in rodent isolated perfused lung.

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