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ChemicalBook >> CAS DataBase List >> TOLAZAMIDE

TOLAZAMIDE

TOLAZAMIDE price.
  • $5 - $1593.9
  • Product name: TOLAZAMIDE
  • CAS: 1156-19-0
  • MF: C14H21N3O3S
  • MW: 311.4
  • EINECS:214-588-3
  • MDL Number:MFCD00083504
  • Synonyms:1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ;1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)-ure ;1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)urea ;4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide ;Tolazamide Solution, 100ppm;diabewas ;n-(((hexahydro-1h-azepin-1-yl)-amino)carbonyl)-4-methyl-benzenesulfonamid ;n-(p-toluenesulfonyl)-n’-hexamethyleniminourea
29 prices
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number2761AH
  • Product descriptionTolazamide
  • Packaging10mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2761AH
  • Product descriptionTolazamide
  • Packaging50mg
  • Price$267
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging10mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging50mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging100mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging250mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging1g
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA899724
  • Product descriptionTolazamide 98+%
  • Packaging5g
  • Price$581
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004439
  • Product descriptionTOLAZAMIDE 95.00%
  • Packaging10MG
  • Price$280.35
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004439
  • Product descriptionTOLAZAMIDE 95.00%
  • Packaging100MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004439
  • Product descriptionTOLAZAMIDE 95.00%
  • Packaging1G
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS691309
  • Product descriptionTolazamide ≥98%
  • Packaging250mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS691309
  • Product descriptionTolazamide ≥98%
  • Packaging1g
  • Price$172
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS691309
  • Product descriptionTolazamide ≥98%
  • Packaging5g
  • Price$530
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT61359
  • Product descriptionTolazamide
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2761AH Tolazamide 10mg $166 2021-12-16 Buy
AK Scientific 2761AH Tolazamide 50mg $267 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 1mg $5 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 10mg $15 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 50mg $32 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 100mg $48 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 250mg $71 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 1g $176 2021-12-16 Buy
Ambeed A899724 Tolazamide 98+% 5g $581 2021-12-16 Buy
American Custom Chemicals Corporation API0004439 TOLAZAMIDE 95.00% 10MG $280.35 2021-12-16 Buy
American Custom Chemicals Corporation API0004439 TOLAZAMIDE 95.00% 100MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0004439 TOLAZAMIDE 95.00% 1G $1593.9 2021-12-16 Buy
Arctom AS691309 Tolazamide ≥98% 250mg $66 2021-12-16 Buy
Arctom AS691309 Tolazamide ≥98% 1g $172 2021-12-16 Buy
Arctom AS691309 Tolazamide ≥98% 5g $530 2021-12-16 Buy
Biosynth Carbosynth FT61359 Tolazamide 10mg $95 2021-12-16 Buy

Properties

Melting point :162-164°C
Boiling point :300°C (rough estimate)
Density :1.2228 (rough estimate)
refractive index :1.6740 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Very slightly soluble in water; freely soluble in chloroform; soluble in acetone; slightly soluble in ethanol (96%).
form :Solid
pka :3.6(at 25℃)
color :White to Off-White
Water Solubility :65.4mg/L(30 ºC)
CAS DataBase Reference :1156-19-0(CAS DataBase Reference)
EPA Substance Registry System :Tolazamide (1156-19-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tolazamide is a first generation sulfonylurea that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2; IC50 = 4.2 μM in HEK293 cells transfected with the human receptor). It has no effect on glucose uptake in L6 rat skeletal muscle cells when used at a concentration of 0.6 mg/mL but enhances glucose uptake two-fold when used in combination with insulin. In vivo, tolazamide (128 mg/kg) reduces glomerulosclerosis and albumin excretion in a rat model of insulin-dependent diabetes induced by streptozotocin . Formulations containing tolazamide have been used in the treatment of type 2 diabetes.

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