SC-514
- $24 - $1802
- Product name: SC-514
- CAS: 354812-17-2
- MF: C9H8N2OS2
- MW: 224.3
- EINECS:
- MDL Number:MFCD00206459
- Synonyms:SC-514, >=98%;3-amino-5-(thiophen-3-yl)thiophene-2-carboxamide;SC-514;GK 01140;IKK-2 Inhibitor, SC-514 ;4-Amino-[2',3'-bithiophene]-5-carboxamide;SC-514;5-(Thien-3-yl)-3-aminothiophene-2-carboxamide;GK 01140
43 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- 1000mg
- ManufacturerAK Scientific
- Product numberSYN5279
- Product descriptionSC-514
- Packaging10mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5279
- Product descriptionSC-514
- Packaging50mg
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging5mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging10mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging50mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging100mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging250mg
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA499215
- Product descriptionSC514 98+%
- Packaging1g
- Price$438
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000534
- Product descriptionSC-514 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000534
- Product descriptionSC-514 95.00%
- Packaging10MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000534
- Product descriptionSC-514 95.00%
- Packaging5MG
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1585
- Product descriptionSC-514
- Packaging10mM(in 1mL DMSO)
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS577703
- Product descriptionSC514 ≥98%
- Packaging5mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS577703
- Product descriptionSC514 ≥98%
- Packaging10mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS577703
- Product descriptionSC514 ≥98%
- Packaging50mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS577703
- Product descriptionSC514 ≥98%
- Packaging100mg
- Price$87
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5279 | SC-514 | 10mg | $86 | 2021-12-16 | Buy |
AK Scientific | SYN5279 | SC-514 | 50mg | $266 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 5mg | $24 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 10mg | $33 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 50mg | $55 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 100mg | $88 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 250mg | $176 | 2021-12-16 | Buy |
Ambeed | A499215 | SC514 98+% | 1g | $438 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000534 | SC-514 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000534 | SC-514 95.00% | 10MG | $704.55 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000534 | SC-514 95.00% | 5MG | $455 | 2021-12-16 | Buy |
ApexBio Technology | B1585 | SC-514 | 10mM(in 1mL DMSO) | $65 | 2021-12-16 | Buy |
Arctom | AS577703 | SC514 ≥98% | 5mg | $24 | 2021-12-16 | Buy |
Arctom | AS577703 | SC514 ≥98% | 10mg | $33 | 2021-12-16 | Buy |
Arctom | AS577703 | SC514 ≥98% | 50mg | $54 | 2021-12-16 | Buy |
Arctom | AS577703 | SC514 ≥98% | 100mg | $87 | 2021-12-16 | Buy |
Properties
Melting point :209-211°C
Boiling point :399.2±42.0 °C(Predicted)
Density :1.450±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :15.63±0.50(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :399.2±42.0 °C(Predicted)
Density :1.450±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :15.63±0.50(Predicted)
form :powder
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
SC-514 is a selective and reversible inhibitor of IKKβ (IKK-2) (IC50 = 3-12 μM) that displays >10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. This compound attenuates NF-κB-induced gene expression of IL-6, IL-8 and Cox-2 (IC50 = 20, 20, and 8 μM, respectively). Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection.Related product price
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