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ChemicalBook >> CAS DataBase List >> Quinidine

Quinidine

Quinidine price.
  • $15 - $660
  • Product name: Quinidine
  • CAS: 56-54-2
  • MF: C20H24N2O2
  • MW: 324.42
  • EINECS:200-279-0
  • MDL Number:MFCD00135581
  • Synonyms:(8R,9S)-6'-Methoxycinchonan-9-ol;CONCHININE;CONQUININE;B-QUININE;(+)-QUINIDINE;QUINIDINE;(+)-QUINDINE;PITAYINE
48 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • Atlantic Research Chemicals
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
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  • 1kg
  • 10mM(in 1mL DMSO)
  • 25gm:
  • ManufacturerAK Scientific
  • Product number6566AF
  • Product descriptionQuinidinemonohydrate
  • Packaging5g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12559
  • Product description(+)-Quinidine
  • Packaging1g
  • Price$21.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12559
  • Product description(+)-Quinidine
  • Packaging5g
  • Price$55.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12559
  • Product description(+)-Quinidine
  • Packaging25g
  • Price$190.65
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7590
  • Product descriptionQuinidine
  • Packaging50mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7590
  • Product descriptionQuinidine
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7590
  • Product descriptionQuinidine
  • Packaging250mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIB1110
  • Product description(+)-Quinidine 98%
  • Packaging5g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIB1110
  • Product description(+)-Quinidine 98%
  • Packaging25g
  • Price$95
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIB1110
  • Product description(+)-Quinidine 98%
  • Packaging100g
  • Price$359
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberAN002904
  • Product description(9S)-6''-Methoxycinchonan-9-ol 95%
  • Packaging25gm:
  • Price$63.62
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594637
  • Product descriptionQuinidine
  • Packaging100mg
  • Price$153
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb594637
  • Product descriptionQuinidine
  • Packaging1000mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM27376
  • Product description6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • Packaging10g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM27376
  • Product description6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • Packaging25g
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM27376
  • Product description6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • Packaging50g
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6566AF Quinidinemonohydrate 5g $80 2021-12-16 Buy
Alfa Aesar A12559 (+)-Quinidine 1g $21.65 2024-03-01 Buy
Alfa Aesar A12559 (+)-Quinidine 5g $55.65 2024-03-01 Buy
Alfa Aesar A12559 (+)-Quinidine 25g $190.65 2024-03-01 Buy
ApexBio Technology B7590 Quinidine 50mg $38 2021-12-16 Buy
ApexBio Technology B7590 Quinidine 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology B7590 Quinidine 250mg $100 2021-12-16 Buy
Apolloscientific BIB1110 (+)-Quinidine 98% 5g $22 2021-12-16 Buy
Apolloscientific BIB1110 (+)-Quinidine 98% 25g $95 2021-12-16 Buy
Apolloscientific BIB1110 (+)-Quinidine 98% 100g $359 2021-12-16 Buy
Atlantic Research Chemicals AN002904 (9S)-6''-Methoxycinchonan-9-ol 95% 25gm: $63.62 2021-12-16 Buy
Biorbyt Ltd orb594637 Quinidine 100mg $153 2021-12-16 Buy
Biorbyt Ltd orb594637 Quinidine 1000mg $221 2021-12-16 Buy
Biosynth Carbosynth FM27376 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol 10g $60 2021-12-16 Buy
Biosynth Carbosynth FM27376 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol 25g $100 2021-12-16 Buy
Biosynth Carbosynth FM27376 6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol 50g $160 2021-12-16 Buy

Properties

Melting point :168-172 °C(lit.)
Boiling point :462.75°C (rough estimate)
alpha :256 º (c=1, EtOH)
Density :1.1294 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :insoluble in H2O; ≥10.32 mg/mL in EtOH with ultrasonic; ≥11.95 mg/mL in DMSO
form :Powder
pka :5.4, 10.0(at 20℃)
color :White to off-white
optical activity :[α]20/D +265±5°, c = 0.8% in ethanol (dry matter)
Water Solubility :0.05 g/100 mL (20 ºC)
Sensitive :Light Sensitive
Merck :14,8060
BRN :91866
BCS Class :1
Stability :Stable. Incompatible with strong oxidizing agents.
LogP :3.440
CAS DataBase Reference :56-54-2(CAS DataBase Reference)
NIST Chemistry Reference :Quinine(56-54-2)
EPA Substance Registry System :Quinidine (56-54-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Quinidine is a commonly used class I antiarrhythmic drug. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree. It exerts its antiarrhythmic effects on the heart by interacting with the electrophysiology mechanisms that cause arrhythmias to modify the abnormalities in impulse initiation and conduction. Quinidine depresses normal automaticity in cardiac fibers that may act as ectopic pacemakers causing arrhythmias. Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.

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