PTC-209 (PTC209
|
- $29 - $1600
- Product name: PTC-209 (PTC209
- CAS: 315704-66-6
- MF: C17H13Br2N5OS
- MW: 495.19
- EINECS:808-910-7
- MDL Number:MFCD02110649
- Synonyms:PTC-209 (PTC209;PTC-209;N-(2,6-dibroMo-4-Methoxyphenyl)-4-(2-MethyliMidazo[1,2-a]pyriMidin-3-yl)thiazol-2-aMine;N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine;N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine PTC-209;PTC-209, >=98%;2-THIAZOLAMINE, N-(2,6-DIBROMO-4-METHOXYPHENYL)-4-(2-METHYLIMIDAZO[1,2-A]PYRIMIDIN-3-YL)-;PTC-209 free base
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 2mg
- 10
- 1mg
- 5MG
- 50
- 10mg
- 25mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2673AH
- Product descriptionN-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine
- Packaging25mg
- Price$477
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0227770
- Product descriptionN-(2,6-DIBROMO-4-METHOXYPHENYL)-4-(2-METHYLIMIDAZO[1,2-A]PYRIMIDIN-3-YL)-1,3-THIAZOL-2-AMINE 95.00%
- Packaging5MG
- Price$495.59
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3179
- Product descriptionPTC-209
- Packaging2mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3179
- Product descriptionPTC-209
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3179
- Product descriptionPTC-209
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3179
- Product descriptionPTC-209
- Packaging10mM(in 1mL DMSO)
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3179
- Product descriptionPTC-209
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181307
- Product descriptionPTC-209 >98%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP165815
- Product descriptionPTC 209 NEW
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBP165815
- Product descriptionPTC 209 NEW
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16277
- Product descriptionPTC-209 ≥95%
- Packaging1mg
- Price$29
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16277
- Product descriptionPTC-209 ≥95%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16277
- Product descriptionPTC-209 ≥95%
- Packaging10mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16277
- Product descriptionPTC-209 ≥95%
- Packaging25mg
- Price$435
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31002274
- Product descriptionPTC-209 98+%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002274
- Product descriptionPTC-209 98+%
- Packaging10mg
- Price$98
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2673AH | N-(2,6-Dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine | 25mg | $477 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0227770 | N-(2,6-DIBROMO-4-METHOXYPHENYL)-4-(2-METHYLIMIDAZO[1,2-A]PYRIMIDIN-3-YL)-1,3-THIAZOL-2-AMINE 95.00% | 5MG | $495.59 | 2021-12-16 | Buy |
| ApexBio Technology | B3179 | PTC-209 | 2mg | $89 | 2021-12-16 | Buy |
| ApexBio Technology | B3179 | PTC-209 | 5mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | B3179 | PTC-209 | 10mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | B3179 | PTC-209 | 10mM(in 1mL DMSO) | $280 | 2021-12-16 | Buy |
| ApexBio Technology | B3179 | PTC-209 | 50mg | $470 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181307 | PTC-209 >98% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP165815 | PTC 209 NEW | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BP165815 | PTC 209 NEW | 50mg | $472.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16277 | PTC-209 ≥95% | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 16277 | PTC-209 ≥95% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16277 | PTC-209 ≥95% | 10mg | $201 | 2024-03-01 | Buy |
| Cayman Chemical | 16277 | PTC-209 ≥95% | 25mg | $435 | 2024-03-01 | Buy |
| Crysdot | CD31002274 | PTC-209 98+% | 5mg | $72 | 2021-12-16 | Buy |
| Crysdot | CD31002274 | PTC-209 98+% | 10mg | $98 | 2021-12-16 | Buy |
Properties
Density :1.86±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :3.77±0.30(Predicted)
form :powder
color :white to brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :315704-66-6
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :3.77±0.30(Predicted)
form :powder
color :white to brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :315704-66-6
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-renewing cell divisions of stem cells in several tissues and can be over-expressed in tumors. PTC-209 is a BMI-1 inhibitor (IC50 = ~ 0.5 μM) that irreversibly impairs colorectal cancer-initiating cell (CIC) growth. It reduces tumor growth in CIC xenograft assays and abrogates colorectal cancer cell self-renewal in vivo, reducing their tumorigenic potential.More related product prices
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