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ChemicalBook >> CAS DataBase List >> Mevastatin

Mevastatin

Mevastatin price.
  • $5 - $1593.9
  • Product name: Mevastatin
  • CAS: 73573-88-3
  • MF: C23H34O5
  • MW: 390.51
  • EINECS:700-442-0
  • MDL Number:MFCD05662341
  • Synonyms:Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-;,8-beta(2s*,4s*),8a-beta))- ;antibioticml236b ;butanoicacid,2-methyl-,1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy ;compactin(penicillium) ;(S)-2-Methylbutyric acid [(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1-yl] ester;2-Methyl-butanoic acid [1S-[1-α(R*),7-β,8-β(2S*,4S*),8a-β]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester;Mevastatin, >=97%
47 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
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  • Usbiological
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  • 25g
  • 5g
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberAPI-1661
  • Product descriptionMevastatin 98%
  • Packaging0.5g
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI518
  • Product descriptionMevastatin
  • Packaging250mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberI518
  • Product descriptionMevastatin
  • Packaging1g
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61357
  • Product descriptionMevastatin, 98%
  • Packaging5mg
  • Price$51.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61357
  • Product descriptionMevastatin, 98%
  • Packaging10mg
  • Price$86.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61357
  • Product descriptionMevastatin, 98%
  • Packaging25mg
  • Price$119.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA445160
  • Product descriptionMevastatin 95%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA445160
  • Product descriptionMevastatin 95%
  • Packaging50mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA445160
  • Product descriptionMevastatin 95%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA445160
  • Product descriptionMevastatin 95%
  • Packaging5g
  • Price$15
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA445160
  • Product descriptionMevastatin 95%
  • Packaging25g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0028920
  • Product descriptionCOMPACTIN 95.00%
  • Packaging1G
  • Price$1593.9
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1788
  • Product descriptionMevastatin
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN90426
  • Product descriptionMevastatin ≥98%
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number3384
  • Product descriptionMevastatin
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3384
  • Product descriptionMevastatin
  • Packaging1g
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1661 Mevastatin 98% 0.5g $370 2021-12-16 Buy
AK Scientific I518 Mevastatin 250mg $63 2021-12-16 Buy
AK Scientific I518 Mevastatin 1g $111 2021-12-16 Buy
Alfa Aesar J61357 Mevastatin, 98% 5mg $51.65 2024-03-01 Buy
Alfa Aesar J61357 Mevastatin, 98% 10mg $86.65 2024-03-01 Buy
Alfa Aesar J61357 Mevastatin, 98% 25mg $119.65 2024-03-01 Buy
Ambeed A445160 Mevastatin 95% 10mg $5 2021-12-16 Buy
Ambeed A445160 Mevastatin 95% 50mg $6 2021-12-16 Buy
Ambeed A445160 Mevastatin 95% 1g $11 2021-12-16 Buy
Ambeed A445160 Mevastatin 95% 5g $15 2021-12-16 Buy
Ambeed A445160 Mevastatin 95% 25g $40 2021-12-16 Buy
American Custom Chemicals Corporation CHM0028920 COMPACTIN 95.00% 1G $1593.9 2021-12-16 Buy
ApexBio Technology B1788 Mevastatin 10mM(in 1mL DMSO) $55 2021-12-16 Buy
Arctom CFN90426 Mevastatin ≥98% 20mg $40 2021-12-16 Buy
AvaChem 3384 Mevastatin 100mg $35 2021-12-16 Buy
AvaChem 3384 Mevastatin 1g $95 2021-12-16 Buy

Properties

Melting point :151-153 °C
alpha :D22 +283° (c = 0.48 in acetone)
Boiling point :555.0±50.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :DMSO: 20 mg/mL
pka :13.49±0.40(Predicted)
form :powder
color :white
λmax :246nm(MeOH)(lit.)
Merck :14,6164
BRN :1269441
InChIKey :AJLFOPYRIVGYMJ-INTXDZFKSA-N
CAS DataBase Reference :73573-88-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) , induces apoptosis which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.

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