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ChemicalBook >> CAS DataBase List >> LX-4211

LX-4211

LX-4211 price.
  • $37 - $1700
  • Product name: LX-4211
  • CAS: 1018899-04-1
  • MF: C21H25ClO5S
  • MW: 424.94
  • EINECS:
  • MDL Number:MFCD22493506
  • Synonyms:LX-4211;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(Methylthio)tetrahydro-2H-pyran-3,4,5-triol;(5S)-Methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-1-thio-beta-L-xylopyranoside;LX4211/LX-4211;LP 802034;LX4211 - L10525;LX-4211 (sotagliflozin);LX-4211, >=98%
18 prices
Selected condition:
Brand
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 5g
  • 100g
  • 250g
  • 500g
  • ManufacturerApexBio Technology
  • Product numberA3567
  • Product descriptionLX-4211
  • Packaging5mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL161424
  • Product descriptionLX4211
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL161424
  • Product descriptionLX4211
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL161424
  • Product descriptionLX4211
  • Packaging100g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL161424
  • Product descriptionLX4211
  • Packaging250g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL161424
  • Product descriptionLX4211
  • Packaging500g
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19141
  • Product descriptionSotagliflozin ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19141
  • Product descriptionSotagliflozin ≥98%
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19141
  • Product descriptionSotagliflozin ≥98%
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19141
  • Product descriptionSotagliflozin ≥98%
  • Packaging25mg
  • Price$573
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM105513
  • Product descriptionsotagliflozin 97%
  • Packaging1g
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105513
  • Product descriptionsotagliflozin 97%
  • Packaging5g
  • Price$1650
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1069
  • Product descriptionSotagliflozin 99.99%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1069
  • Product descriptionSotagliflozin 99.99%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1069
  • Product descriptionSotagliflozin 99.99%
  • Packaging25mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1069
  • Product descriptionSotagliflozin 99.99%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology A3567 LX-4211 5mg $165 2021-12-16 Buy
Biosynth Carbosynth BL161424 LX4211 25mg $75 2021-12-16 Buy
Biosynth Carbosynth BL161424 LX4211 50mg $100 2021-12-16 Buy
Biosynth Carbosynth BL161424 LX4211 100g $150 2021-12-16 Buy
Biosynth Carbosynth BL161424 LX4211 250g $300 2021-12-16 Buy
Biosynth Carbosynth BL161424 LX4211 500g $500 2021-12-16 Buy
Cayman Chemical 19141 Sotagliflozin ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 19141 Sotagliflozin ≥98% 5mg $161 2024-03-01 Buy
Cayman Chemical 19141 Sotagliflozin ≥98% 10mg $283 2024-03-01 Buy
Cayman Chemical 19141 Sotagliflozin ≥98% 25mg $573 2024-03-01 Buy
Chemenu CM105513 sotagliflozin 97% 1g $550 2021-12-16 Buy
Chemenu CM105513 sotagliflozin 97% 5g $1650 2021-12-16 Buy
ChemScene CS-1069 Sotagliflozin 99.99% 5mg $100 2021-12-16 Buy
ChemScene CS-1069 Sotagliflozin 99.99% 10mg $150 2021-12-16 Buy
ChemScene CS-1069 Sotagliflozin 99.99% 25mg $290 2021-12-16 Buy
ChemScene CS-1069 Sotagliflozin 99.99% 50mg $450 2021-12-16 Buy

Properties

Boiling point :607.9±55.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:84.0(Max Conc. mg/mL);197.67(Max Conc. mM)
Ethanol:17.0(Max Conc. mg/mL);40.01(Max Conc. mM) pka :12.87±0.70(Predicted)
form :Powder
color :White to off-white
InChIKey :QKDRXGFQVGOQKS-WFCPIQDQNA-N
SMILES :[C@@H]1(C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)O[C@H](SC)[C@@H](O)[C@H](O)[C@H]1O |&1:0,19,22,24,26,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Inhibiting renal glucose reabsorption through the sodium-glucose cotransporter (SGLT) offers an insulin-independent alternative to controlling blood glucose concentrations in patients with type 2 diabetes. While the majority of glucose is reabsorbed from glomerular filtrate by SGLT2, which is predominantly expressed in the kidney S1 segment of the proximal tubule, SGLT1 reabsorbs glucose in the distal S3 segment of the renal proximal tubule as well as from the small intestine. Sotagliflozin is an orally available L-xyloside that potently inhibits both SGLT1 and SGLT2 (IC50s = 36 and 1.8 nM, respectively, for human isoforms in vitro). It improves glycemic control in nonobese diabetes prone mice with type 1 diabetes and in patients with type 2 diabetes in a randomized, placebo-controlled clinical trial. Sotagliflozin also increases serum glucagon-like peptide 1 and peptide YY levels by reducing SGLT1-mediated absorption of intestinal glucose.