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ChemicalBook >> CAS DataBase List >> HS-173

HS-173

HS-173 price.
  • $37 - $2691.1
  • Product name: HS-173
  • CAS: 1276110-06-5
  • MF: C21H18N4O4S
  • MW: 422.46
  • EINECS:
  • MDL Number:MFCD28023584
  • Synonyms:ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate;6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester HS-173;HS-173;6-[5-[(Phenylsulfonyl)amino]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;HS 173;HS173;CS-1007;HS-173, 98%, a novel PI3K inhibitor;Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester
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  • Ambeed
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging25mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA336342
  • Product descriptionHS-173 97%
  • Packaging50mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181255
  • Product descriptionHS-173 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181255
  • Product descriptionHS-173 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181255
  • Product descriptionHS-173 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19156
  • Product descriptionHS-173 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19156
  • Product descriptionHS-173 ≥98%
  • Packaging5mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19156
  • Product descriptionHS-173 ≥98%
  • Packaging10mg
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19156
  • Product descriptionHS-173 ≥98%
  • Packaging25mg
  • Price$397
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6015
  • Product descriptionHS-173 99.04%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6015
  • Product descriptionHS-173 99.04%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6015
  • Product descriptionHS-173 99.04%
  • Packaging25mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6015
  • Product descriptionHS-173 99.04%
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11301818
  • Product descriptionHS-173 97%
  • Packaging25mg
  • Price$295
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A336342 HS-173 97% 5mg $65 2021-12-16 Buy
Ambeed A336342 HS-173 97% 10mg $85 2021-12-16 Buy
Ambeed A336342 HS-173 97% 25mg $111 2021-12-16 Buy
Ambeed A336342 HS-173 97% 50mg $145 2021-12-16 Buy
Biorbyt Ltd orb181255 HS-173 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb181255 HS-173 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb181255 HS-173 >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 19156 HS-173 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 19156 HS-173 ≥98% 5mg $108 2024-03-01 Buy
Cayman Chemical 19156 HS-173 ≥98% 10mg $195 2024-03-01 Buy
Cayman Chemical 19156 HS-173 ≥98% 25mg $397 2024-03-01 Buy
ChemScene CS-6015 HS-173 99.04% 5mg $96 2021-12-16 Buy
ChemScene CS-6015 HS-173 99.04% 10mg $168 2021-12-16 Buy
ChemScene CS-6015 HS-173 99.04% 25mg $348 2021-12-16 Buy
ChemScene CS-6015 HS-173 99.04% 50mg $540 2021-12-16 Buy
Crysdot CD11301818 HS-173 97% 25mg $295 2021-12-16 Buy

Properties

Melting point :>193°C (dec.)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly)
pka :6.84±0.40(Predicted)
form :Solid
color :Grey to Brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

HS-173 is an imidazopyridine analog that acts as a PI3Kα inhibitor with an IC50 value of 0.8 nM. It demonstrates antiproliferative activity in T47D, SK-BR-3, and MCF-7 cells with IC50 values of 0.6, 1.5, and 7.8 μM, respectively. HS-173 is reported to induce apoptosis by arresting the cell cycle at the G2/M phase and by activating caspases. It has also been shown to block VEGF-induced angiogenesis both in vitro and in vivo.