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ChemicalBook >> CAS DataBase List >> Cephalothin

Cephalothin

Cephalothin price.
  • $6 - $832.02
  • Product name: Cephalothin
  • CAS: 153-61-7
  • MF: C16H16N2O6S2
  • MW: 396.44
  • EINECS:205-815-7
  • MDL Number:MFCD00242614
  • Synonyms:CEPHALOTHIN;(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-[2-(2-thienyl)acetylamino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;C07761;(6R,7R)-3-[(acetyloxy)Methyl]-8-oxo-7-[2-(thiophen-2-yl)acetaMido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-3-[(Acetyloxy)Methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]aMino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;(6R)-3-acetoxyMethyl-8-oxo-7t-(2-thiophen-2-yl-acetylaMino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, (6R,7R)-
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  • AK Scientific
  • Alfa Aesar
  • Alichem
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • TRC
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  • 25mg
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  • ManufacturerAK Scientific
  • Product numberJ95251
  • Product descriptionCephalothin
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10773
  • Product descriptionCephalothin
  • Packaging25mg
  • Price$38.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH36175
  • Product descriptionCephalothin (acid) 97%
  • Packaging5g
  • Price$92.9
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH36175
  • Product descriptionCephalothin (acid) 97%
  • Packaging25g
  • Price$249.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlichem
  • Product number153617
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
  • Packaging100g
  • Price$299.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number153617
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
  • Packaging500g
  • Price$832.02
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging10g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging25g
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging100g
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA437484
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging500g
  • Price$515
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7926
  • Product descriptionCephalothin
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7926
  • Product descriptionCephalothin
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS097741
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS097741
  • Product description(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97%
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J95251 Cephalothin 5g $15 2021-12-16 Buy
AK Scientific J10773 Cephalothin 25mg $38.6 2021-12-16 Buy
Alfa Aesar H36175 Cephalothin (acid) 97% 5g $92.9 2023-06-20 Buy
Alfa Aesar H36175 Cephalothin (acid) 97% 25g $249.65 2024-03-01 Buy
Alichem 153617 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 100g $299.98 2021-12-16 Buy
Alichem 153617 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 500g $832.02 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 1g $6 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 5g $15 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 10g $21 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 25g $43 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 100g $138 2021-12-16 Buy
Ambeed A437484 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 500g $515 2021-12-16 Buy
ApexBio Technology B7926 Cephalothin 100mg $50 2021-12-16 Buy
ApexBio Technology B7926 Cephalothin 500mg $100 2021-12-16 Buy
Arctom AS097741 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 1g $6 2021-12-16 Buy
Arctom AS097741 (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 97% 5g $15 2021-12-16 Buy

Properties

Melting point :160-161 ºC
alpha :D20 +50° (c = 1.03 in acetonitrile)
Boiling point :757.2±60.0 °C(Predicted)
Density :1.4162 (rough estimate)
refractive index :1.6510 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Sparingly), Dioxane (Slightly), Methanol (Slightly)
form :Solid
pka :pKa 2.5 (Uncertain)
color :White to Off-White
Water Solubility :158 MG/L
λmax :263nm(H2O)(lit.)
Merck :14,1982
CAS DataBase Reference :153-61-7(CAS DataBase Reference)
EPA Substance Registry System :Cephalothin (153-61-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P285 In case of inadequate ventilation wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P403 Store in a well-ventilated place.

Description

Cephalothin is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

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