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ChemicalBook >> CAS DataBase List >> Betulinic acid

Betulinic acid

Betulinic acid  price.
  • $5 - $904.94
  • Product name: Betulinic acid
  • CAS: 472-15-1
  • MF: C30H48O3
  • MW: 456.71
  • EINECS:207-448-8
  • MDL Number:MFCD00009619
  • Synonyms:3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID;3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID;3B-HYDROXY-20(29)-LUPENE-28-OIC ACID;Birch bark extract/β-Amyrin/betulinic acid;3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID;BETULINIC ACID;LUP-20(29)-EN-28-OIC ACID, 3-HYDROXY-, (3B)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-
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  • Adipogen Life Sciences
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  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0417-M500
  • Product descriptionBetulinicacid(>97%) ≥97%(HPLC)
  • Packaging500mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-47879
  • Product descriptionBetulinic acid 98%
  • Packaging1g
  • Price$830
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number2267AH
  • Product descriptionBetulinic acid
  • Packaging5g
  • Price$321
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging50mg
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging100mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging5g
  • Price$90
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging10g
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200416
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+%
  • Packaging25g
  • Price$170
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045790
  • Product descriptionBETULINIC ACID 95.00%
  • Packaging5MG
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045790
  • Product descriptionBETULINIC ACID 95.00%
  • Packaging1G
  • Price$904.94
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3237
  • Product descriptionBetulinic acid
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019600
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS019600
  • Product description(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98%
  • Packaging50mg
  • Price$7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0417-M500 Betulinicacid(>97%) ≥97%(HPLC) 500mg $185 2021-12-16 Buy
AHH MT-47879 Betulinic acid 98% 1g $830 2021-12-16 Buy
AK Scientific 2267AH Betulinic acid 5g $321 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 25mg $5 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 50mg $7 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 100mg $9 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 250mg $11 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 1g $11 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 5g $90 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 10g $90 2021-12-16 Buy
Ambeed A200416 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid 98+% 25g $170 2021-12-16 Buy
American Custom Chemicals Corporation API0045790 BETULINIC ACID 95.00% 5MG $510 2021-12-16 Buy
American Custom Chemicals Corporation API0045790 BETULINIC ACID 95.00% 1G $904.94 2021-12-16 Buy
ApexBio Technology A3237 Betulinic acid 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS019600 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98% 25mg $5 2021-12-16 Buy
Arctom AS019600 (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylicacid ≥98% 50mg $7 2021-12-16 Buy

Properties

Melting point :295-298 °C (dec.) (lit.)
Boiling point :550.0±33.0 °C(Predicted)
alpha :D25 +7.5° (c = 0.37 in pyridine)
Density :1.065±0.06 g/cm3(Predicted)
refractive index :7.8 ° (C=0.9, Pyridine)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :Solid
pka :4.61±0.70(Predicted)
color :White or off-white
optical activity :[α]20/D +7.8°, c = 0.9 in pyridine
Merck :14,1190
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :QGJZLNKBHJESQX-FZFNOLFKSA-N
LogP :7.653 (est)
CAS DataBase Reference :472-15-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Betulinic acid is a natural plant triterpenoid that is structurally related to mammalian bile acids. It is an agonist of the G protein-coupled bile acid receptor TGR5 (EC50 = 1 μM), which might be linked with its ability to alter gene expression and fatty liver development in cells and mice given ethanol. Betulinic acid also reduces NF-κB signaling and expression of microRNA-33 in LPS-treated macrophages, increasing levels of the ATP-binding cassette (ABC) cholesterol transporter ABCA1. It also inhibits replication of HIV-1 (IC50 = 1.4 μM) and has cytotoxic effects against cancer cells.

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