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ChemicalBook >> CAS DataBase List >> Bestatin

Bestatin

Bestatin price.
  • $18 - $18700
  • Product name: Bestatin
  • CAS: 58970-76-6
  • MF: C16H24N2O4
  • MW: 308.37
  • EINECS:261-529-2
  • MDL Number:MFCD00083262
  • Synonyms:UbenaMix, Inobestin, NK 421;L-Leucine,N-[(2S,3R)-3-aMino-2-hydroxy-1-oxo-4-phenylbutyl]-;N-[(2S,3R)-3-AMino-2-hydroxy-4-phenylbutyryl]-L-leucine 97%;3-(r)-amino-2-(s)-hydroxy-4-phenylbutanoyl-(s)-leucine ;n-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-,(s-(r*,s*))-l-leucin ;nk421 ;N-[(2S,3R)-3-AMINO-2-HYDROXY-1-OXO-4-PHENYLBUTYL]-L-LEUCINE;N-((2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRYL)-L-LEUCINE
58 prices
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  • Activate Scientific
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • AvaChem
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  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
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  • Sigma-Aldrich
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  • Usbiological
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  • ManufacturerActivate Scientific
  • Product numberAS112176
  • Product descriptionBestatin 98%
  • Packaging250mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS112176
  • Product descriptionBestatin 98%
  • Packaging1g
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberC829
  • Product descriptionN-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
  • Packaging250mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98810
  • Product descriptionN-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
  • Packaging500mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98810
  • Product descriptionN-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
  • Packaging1g
  • Price$319
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ61106
  • Product descriptionBestatin
  • Packaging100mg
  • Price$89.2
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ61106
  • Product descriptionBestatin
  • Packaging250mg
  • Price$175
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA147735
  • Product description(S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+%
  • Packaging100mg
  • Price$18
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147735
  • Product description(S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+%
  • Packaging250mg
  • Price$36
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147735
  • Product description(S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+%
  • Packaging1g
  • Price$97
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA147735
  • Product description(S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+%
  • Packaging5g
  • Price$387
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2575
  • Product descriptionBestatin
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2575
  • Product descriptionBestatin
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2575
  • Product descriptionBestatin
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2575
  • Product descriptionBestatin
  • Packaging25mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2575
  • Product descriptionBestatin
  • Packaging100mg
  • Price$340
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS112176 Bestatin 98% 250mg $189 2021-12-16 Buy
Activate Scientific AS112176 Bestatin 98% 1g $378 2021-12-16 Buy
AK Scientific C829 N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine 250mg $195 2021-12-16 Buy
AK Scientific J98810 N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine 500mg $260 2021-12-16 Buy
AK Scientific J98810 N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine 1g $319 2021-12-16 Buy
Alfa Aesar J61106 Bestatin 100mg $89.2 2024-03-01 Buy
Alfa Aesar J61106 Bestatin 250mg $175 2024-03-01 Buy
Ambeed A147735 (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+% 100mg $18 2021-12-16 Buy
Ambeed A147735 (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+% 250mg $36 2021-12-16 Buy
Ambeed A147735 (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+% 1g $97 2021-12-16 Buy
Ambeed A147735 (S)-2-((2S,3R)-3-Amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoicacid 98+% 5g $387 2021-12-16 Buy
ApexBio Technology A2575 Bestatin 1unit $28 2021-12-16 Buy
ApexBio Technology A2575 Bestatin 5mg $50 2021-12-16 Buy
ApexBio Technology A2575 Bestatin 10mg $70 2021-12-16 Buy
ApexBio Technology A2575 Bestatin 25mg $120 2021-12-16 Buy
ApexBio Technology A2575 Bestatin 100mg $340 2021-12-16 Buy

Properties

Melting point :245 °C (dec.)(lit.)
alpha :D20 -15.5° (c = 1.0 in 1N HCl)
Boiling point :448.76°C (rough estimate)
Density :1.0917 (rough estimate)
refractive index :1.5800 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Aqueous Acid (Slightly, Sonicated), DMSO (Slightly, Heated)
pka :8.1, 3.1(at 25℃)
form :Powder
color :White
optical activity :[α]20/D 11°, c = 1 in 1 M NaOH
Water Solubility :Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq. NaOH (50 mM), ethanol (<1 mg/ml at 25°C), acetic acid, aq. HCl, and alkaline solution. Insoluble in ethyl acetate, benzene, hexane, and chloroform.
Merck :13,9910
InChIKey :VGGGPCQERPFHOB-RDBSUJKOSA-N
CAS DataBase Reference :58970-76-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Bestatin can indirectly act on monocytes by inhibiting Aminopeptidase B, which in turn inhibits the catabolism of tuftsin. Bestatin has also been shown to inhibit Leukotriene A4?hydrolase. It can directly stimulate lymphocytes through its fixation on the cell surface. The agent has been used in multiple leukemia studies. Bestatin is an aminopeptidase inhibitor, inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.

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