AKTI-1/2
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- $29 - $2200
- Product name: AKTI-1/2
- CAS: 612847-09-3
- MF: C34H29N7O
- MW: 551.64
- EINECS:1592732-453-0
- MDL Number:MFCD09026909
- Synonyms:1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-;AKT inhibitor VIII (AKTI-1/2);1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)-piperidin-4-yl)-1H-benzo[d]imidazol-2(;1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
37 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 500μg
- 1MG
- 2mg
- 2.5MG
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- 10mM(in 1mL DMSO)
- 250mg
- ManufacturerAK Scientific
- Product numberX2144
- Product descriptionAKT Inhibitor VIII
- Packaging250mg
- Price$1454
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000362
- Product descriptionAKTI-1/2 INHIBITOR 95.00%
- Packaging1MG
- Price$240.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000362
- Product descriptionAKTI-1/2 INHIBITOR 95.00%
- Packaging2.5MG
- Price$715
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000362
- Product descriptionAKTI-1/2 INHIBITOR 95.00%
- Packaging25MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3149
- Product descriptionAKT Inhibitor VIII
- Packaging10mM(in 1mL DMSO)
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3149
- Product descriptionAKT Inhibitor VIII
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3149
- Product descriptionAKT Inhibitor VIII
- Packaging25mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2540
- Product descriptionAktInhibitorVIII-Akti-1/2 98%
- Packaging25mg
- Price$368.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17246
- Product descriptionAkti-1/2
- Packaging1mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17246
- Product descriptionAkti-1/2
- Packaging2mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17246
- Product descriptionAkti-1/2
- Packaging5mg
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17246
- Product descriptionAkti-1/2
- Packaging10mg
- Price$570
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17246
- Product descriptionAkti-1/2
- Packaging25mg
- Price$1135
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14870
- Product descriptionAkt Inhibitor VIII ≥98%
- Packaging500μg
- Price$29
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14870
- Product descriptionAkt Inhibitor VIII ≥98%
- Packaging1mg
- Price$55
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14870
- Product descriptionAkt Inhibitor VIII ≥98%
- Packaging5mg
- Price$128
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X2144 | AKT Inhibitor VIII | 250mg | $1454 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000362 | AKTI-1/2 INHIBITOR 95.00% | 1MG | $240.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000362 | AKTI-1/2 INHIBITOR 95.00% | 2.5MG | $715 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000362 | AKTI-1/2 INHIBITOR 95.00% | 25MG | $1963.5 | 2021-12-16 | Buy |
| ApexBio Technology | A3149 | AKT Inhibitor VIII | 10mM(in 1mL DMSO) | $130 | 2021-12-16 | Buy |
| ApexBio Technology | A3149 | AKT Inhibitor VIII | 10mg | $145 | 2021-12-16 | Buy |
| ApexBio Technology | A3149 | AKT Inhibitor VIII | 25mg | $350 | 2021-12-16 | Buy |
| Axon Medchem | Axon2540 | AktInhibitorVIII-Akti-1/2 98% | 25mg | $368.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17246 | Akti-1/2 | 1mg | $220 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17246 | Akti-1/2 | 2mg | $330 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17246 | Akti-1/2 | 5mg | $375 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17246 | Akti-1/2 | 10mg | $570 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA17246 | Akti-1/2 | 25mg | $1135 | 2021-12-16 | Buy |
| Cayman Chemical | 14870 | Akt Inhibitor VIII ≥98% | 500μg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 14870 | Akt Inhibitor VIII ≥98% | 1mg | $55 | 2024-03-01 | Buy |
| Cayman Chemical | 14870 | Akt Inhibitor VIII ≥98% | 5mg | $128 | 2024-03-01 | Buy |
Properties
Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3
Safety Information
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Description
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.More related product prices
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