3-METHYLADENINE
- $20 - $1890
- Product name: 3-METHYLADENINE
- CAS: 5142-23-4
- MF: C6H7N5
- MW: 149.15
- EINECS:225-908-6
- MDL Number:MFCD00010531
- Synonyms:3H-Purin-6-amine, 3-methyl-;3-methyl-3h-purin-6-amin ;3-Methyl-3H-purin-6-amine;3-methyl-adenin ;Adenine, 3-methyl-;3-METHYLADENINE;3-methyl-3H-adenine ;6-AMINO-3-METHYLPURINE
46 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 25mg
- 10mg
- 50
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 200mg
- 250mg
- 0.5g
- 500mg
- 1000mg
- 1g
- 5g
- 10g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0203-M025
- Product description3-Methyladenine ≥98%(HPLC)
- Packaging25mg
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-17316
- Product description3-Methyladenine 98%
- Packaging0.5g
- Price$298
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX5709
- Product description3-Methyladenine
- Packaging25mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11161
- Product descriptionAutophagy Inhibitor, 3-MA
- Packaging100mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64813
- Product descriptionAutophagy Inhibitor, 3-MA
- Packaging25mg
- Price$66.3
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64813
- Product descriptionAutophagy Inhibitor, 3-MA
- Packaging50mg
- Price$111
- Updated2023-06-20
- Buy
- ManufacturerApexBio Technology
- Product numberA8353
- Product description3-Methyladenine
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8353
- Product description3-Methyladenine
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8353
- Product description3-Methyladenine
- Packaging200mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8353
- Product description3-Methyladenine
- Packaging500mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberOR470734
- Product description3-Methyladenine
- Packaging10mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016753
- Product description3-Methyl-3H-purin-6-amine ≥98%
- Packaging50mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016753
- Product description3-Methyl-3H-purin-6-amine ≥98%
- Packaging100mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016753
- Product description3-Methyl-3H-purin-6-amine ≥98%
- Packaging250mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60037
- Product description3-Methyladenine ≥98%
- Packaging20mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016753
- Product description3-Methyl-3H-purin-6-amine ≥98%
- Packaging1g
- Price$60
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | CDX-M0203-M025 | 3-Methyladenine ≥98%(HPLC) | 25mg | $41 | 2021-12-16 | Buy |
AHH | MT-17316 | 3-Methyladenine 98% | 0.5g | $298 | 2021-12-16 | Buy |
AK Scientific | X5709 | 3-Methyladenine | 25mg | $33 | 2021-12-16 | Buy |
AK Scientific | J11161 | Autophagy Inhibitor, 3-MA | 100mg | $95 | 2021-12-16 | Buy |
Alfa Aesar | J64813 | Autophagy Inhibitor, 3-MA | 25mg | $66.3 | 2023-06-20 | Buy |
Alfa Aesar | J64813 | Autophagy Inhibitor, 3-MA | 50mg | $111 | 2023-06-20 | Buy |
ApexBio Technology | A8353 | 3-Methyladenine | 50mg | $50 | 2021-12-16 | Buy |
ApexBio Technology | A8353 | 3-Methyladenine | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | A8353 | 3-Methyladenine | 200mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | A8353 | 3-Methyladenine | 500mg | $240 | 2021-12-16 | Buy |
Apolloscientific | OR470734 | 3-Methyladenine | 10mg | $27 | 2021-12-16 | Buy |
Arctom | AS016753 | 3-Methyl-3H-purin-6-amine ≥98% | 50mg | $20 | 2021-12-16 | Buy |
Arctom | AS016753 | 3-Methyl-3H-purin-6-amine ≥98% | 100mg | $25 | 2021-12-16 | Buy |
Arctom | AS016753 | 3-Methyl-3H-purin-6-amine ≥98% | 250mg | $34 | 2021-12-16 | Buy |
Arctom | CFN60037 | 3-Methyladenine ≥98% | 20mg | $50 | 2021-12-16 | Buy |
Arctom | AS016753 | 3-Methyl-3H-purin-6-amine ≥98% | 1g | $60 | 2021-12-16 | Buy |
Properties
Melting point :~300 °C (dec.)(lit.)
Boiling point :240℃
Density :1.60
refractive index :1.8070 (estimate)
Flash point :99℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
pka :6.77±0.20(Predicted)
form :Powder
color :White
BRN :146087
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Boiling point :240℃
Density :1.60
refractive index :1.8070 (estimate)
Flash point :99℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
pka :6.77±0.20(Predicted)
form :Powder
color :White
BRN :146087
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Precautionary statements: |
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Description
Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms. mTOR, whose activation is controlled by phosphoinositide 3-kinase (PI3K), is a key regulator of autophagy. 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome. At 5 mM, 3-MA inhibits protein degradation in rat hepatocytes by 65%. 3-MA has been shown to block class I, class II, and class III PI3Ks, including some downstream targets, and to suppress the invasion of highly metastatic human fibrosarcoma HT1080 cells at 10 mM.More related product prices
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