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ChemicalBook >> CAS DataBase List >> NSC632839hydrochloride

NSC632839hydrochloride

NSC632839hydrochloride price.
  • $32 - $1100
  • Product name: NSC632839hydrochloride
  • CAS: 157654-67-6
  • MF: C21H21NO.ClH
  • MW: 339.864
  • EINECS:604-604-1
  • MDL Number:MFCD09753281
  • Synonyms:Ubiquitin Isopeptidase Inhibitor II, F6;NSC 632839;4-Piperidione,3,5-bis[(4-methylphenyl)methylene] hydrochloride;NSC632839hydrochloride;3,5-Bis[(4-methylphenyl)methylene]-4-piperidonehydrochloride;NSC 632839;NSC-632839;Ubiquitin Isopeptidase Inhibitor II;NSC632839 HCl
34 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2599AH
  • Product description4-Piperidione,3,5-bis[(4-methylphenyl)methylene]hydrochloride
  • Packaging100mg
  • Price$702
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging5mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging50mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging100mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging250mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA457204
  • Product descriptionNSC632839Hydrochloride 98+%
  • Packaging1g
  • Price$637
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001198
  • Product descriptionNSC 632839 HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$500.18
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4004
  • Product descriptionNSC632839hydrochloride
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4004
  • Product descriptionNSC632839hydrochloride
  • Packaging50mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16893
  • Product descriptionNSC 632839 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16893
  • Product descriptionNSC 632839 ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16893
  • Product descriptionNSC 632839 ≥98%
  • Packaging25mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16893
  • Product descriptionNSC 632839 ≥98%
  • Packaging50mg
  • Price$305
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM249826
  • Product description3,5-Bis(4-methylbenzylidene)piperidin-4-onehydrochloride 98%
  • Packaging100mg
  • Price$413
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2599AH 4-Piperidione,3,5-bis[(4-methylphenyl)methylene]hydrochloride 100mg $702 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 5mg $43 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 10mg $58 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 25mg $75 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 50mg $98 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 100mg $127 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 250mg $255 2021-12-16 Buy
Ambeed A457204 NSC632839Hydrochloride 98+% 1g $637 2021-12-16 Buy
American Custom Chemicals Corporation INB0001198 NSC 632839 HYDROCHLORIDE 95.00% 5MG $500.18 2021-12-16 Buy
ApexBio Technology A4004 NSC632839hydrochloride 10mg $70 2021-12-16 Buy
ApexBio Technology A4004 NSC632839hydrochloride 50mg $230 2021-12-16 Buy
Cayman Chemical 16893 NSC 632839 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 16893 NSC 632839 ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 16893 NSC 632839 ≥98% 25mg $230 2024-03-01 Buy
Cayman Chemical 16893 NSC 632839 ≥98% 50mg $305 2024-03-01 Buy
Chemenu CM249826 3,5-Bis(4-methylbenzylidene)piperidin-4-onehydrochloride 98% 100mg $413 2021-12-16 Buy

Properties

storage temp. :Store at +4°C
solubility :DMSO: ≥2mg/mL (warmed)
form :powder
color :faint yellow to dark yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protein ubiquitination is a dynamic process that can be reversed by deubiquitinating enzymes (DUBs) that remove ubiquitin from proteins, sparing them from degradation by the proteasome. The DUBs have been divided into various groups, the largest being the ubiquitin-specific proteases (USPs). NSC 632839 inhibits USP2 and USP7 as well as the ubiquitin-like SUMO peptidase SENP2 with EC50 values of 45, 37, and 9.8 μM, respectively. It is reported to inhibit apoptosis through a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 = 15.7 μM in cells sensitized by E1A, an adenoviral oncogene).

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