[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
- $32 - $2171
- Product name: [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
- CAS: 1360705-96-9
- MF: C22H20Cl2N4O4
- MW: 475.32
- EINECS:
- MDL Number:MFCD22666407
- Synonyms:[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;CID 49766530;ML 210;[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;ML 210 - CID 49766530;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;ML 210 >=98% (HPLC);(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
22 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
Package
- 5mg
- 10
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3040DH
- Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3040DH
- Product description[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone
- Packaging50mg
- Price$498
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging5mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging100mg
- Price$473
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging250mg
- Price$977
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA824339
- Product description(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+%
- Packaging1g
- Price$2171
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2017
- Product descriptionML210-CID49766530 100%
- Packaging10mg
- Price$126.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546193
- Product descriptionML 210 >98%
- Packaging10mg
- Price$198.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546193
- Product descriptionML 210 >98%
- Packaging50mg
- Price$513.4
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM170835
- Product descriptionML 210
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM170835
- Product descriptionML 210
- Packaging50mg
- Price$332.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23282
- Product descriptionML 210 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23282
- Product descriptionML 210 ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23282
- Product descriptionML 210 ≥98%
- Packaging10mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23282
- Product descriptionML 210 ≥98%
- Packaging25mg
- Price$449
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0017911
- Product descriptionML 210 99.92%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3040DH | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone | 10mg | $178 | 2021-12-16 | Buy |
AK Scientific | 3040DH | [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]-(5-methyl-4-nitro-3-isoxazolyl)methanone | 50mg | $498 | 2021-12-16 | Buy |
Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 5mg | $69 | 2021-12-16 | Buy |
Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 100mg | $473 | 2021-12-16 | Buy |
Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 250mg | $977 | 2021-12-16 | Buy |
Ambeed | A824339 | (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone 98+% | 1g | $2171 | 2021-12-16 | Buy |
Axon Medchem | Axon2017 | ML210-CID49766530 100% | 10mg | $126.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546193 | ML 210 >98% | 10mg | $198.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546193 | ML 210 >98% | 50mg | $513.4 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM170835 | ML 210 | 10mg | $95 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM170835 | ML 210 | 50mg | $332.5 | 2021-12-16 | Buy |
Cayman Chemical | 23282 | ML 210 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 23282 | ML 210 ≥98% | 5mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 23282 | ML 210 ≥98% | 10mg | $214 | 2024-03-01 | Buy |
Cayman Chemical | 23282 | ML 210 ≥98% | 25mg | $449 | 2024-03-01 | Buy |
ChemScene | CS-0017911 | ML 210 99.92% | 5mg | $90 | 2021-12-16 | Buy |
Properties
Boiling point :644.7±55.0 °C(Predicted)
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.415±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 30 mg/ml)
pka :4.69±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Description
ML210 (CAS 1360705-96-9) is selectively synthetic lethal to HRAS expressing cells compared to isogenic non-HRAS cells (IC50?= 7.1 nM for BJeLR (expressing HRASg12v) cells vs IC50?= 272 nM for BJeH-LT (non-HRAS expressing) cells.1?ML210 is able to inhibit glutathione peroxidase 4 (GPX4), an important selenoenzyme that protects cells from ferroptosis caused by iron catalyzed formation of free radicals from lipid peroxides.2,3?Treatment of several treatment-resistant cancer cell lines exhibiting a high mesenchymal state with ML210 resulted in selective induction of ferroptosis.3Related product price
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