Ethylene glycol
Product identifier
- Product name: Ethylene glycol
- CBnumber: CB7852707
- CAS: 107-21-1
- EINECS Number: 203-473-3
- Synonyms: ethylene glycol,Monoethylene glycol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
Substance
- Product name: Ethylene glycol
- Synonyms: ethylene glycol,Monoethylene glycol
- CAS: 107-21-1
- EC number: 203-473-3
- MF: C2H6O2
- MW: 62.07
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.
Hygroscopic.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsHandle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolourless liquid
- Odourodourless
- Odour ThresholdNo data available
- pH6-7.5 (100g/l, H2O, 20℃)
- Melting point/freezing pointMelting point/range: -13 °C
- Initial boiling point and boiling range196 - 198 °C
- Flash point111 °C - closed cup115 °C - open cup
- Evaporation rate1
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 15,3 %(V) Lower explosion limit: 3,2 %(V)
- Vapour pressure1 hPa at 51,1 °C
- Vapour density2,14 - (Air = 1.0)
- Relative density1,113 g/mL at 25 °C
- Water solubilitycompletely miscible
- Partition coefficient: n-octanol/waterlog Pow: -1,36 - Bioaccumulation is not expected.
- Autoignition temperature412 °C at 1.013 hPa
- Decomposition temperatureNo data available
- ViscosityNo data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- λmaxλ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.01
Other safety information
Surface tension 48,4 mN/m at 20 °C
Relative vapour density
2,14 - (Air = 1.0)
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
No data available
Incompatible materials
Strong acids, Strong oxidizing agents, Strong bases, Aldehydes, Aluminum
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male and female - 6 h - > 2,5 mg/l Remarks: (ECHA)
LD50 Dermal - Mouse - male and female - > 3.500 mg/kg Remarks: (ECHA)
Result: No skin irritation - 20 h Remarks: (ECHA)
Result: No eye irritation - 24 h Remarks: (ECHA)
Result: negative
(OECD Test Guideline 406)
Escherichia coli/Salmonella typhimurium Result: negative
Rat - male and female Result: negative
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Overexposure may cause reproductive disorder(s) based on tests with laboratory animals.
When ingested early symptoms mimic alcohol inebriation and are followed by nausea, vomiting, abdominal pain, weakness, muscle tenderness, respiratory failure, convulsions, cardiovascular collapse, pulmonary edema, hypocalcemic tetany, and severe metabolic acidosis. Without treatment, death may occur in 8 to 24 hours. Victims who survive the initial toxicity period usually develop renal failure along with brain and liver damage., Exposure to and/or consumption of alcohol may increase toxic effects.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
agitation, CNS disorders Systemic effects:
After a latency period:
Tiredness, ataxia (impaired locomotor coordination), Unconsciousness Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice. Central nervous system - Irregularities - Based on Human Evidence
Toxicity
(US-EPA)
static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h (OECD Test Guideline 202)
Remarks: (Lit.)
Persistence and degradability
Biodegradability aerobic - Exposure time 10 d
Result: 90 - 100 % - Readily biodegradable. (OECD Test Guideline 301A)
Biochemical Oxygen Demand (BOD)
Chemical Oxygen Demand (COD)
Theoretical oxygen demand
780 mg/g Remarks: (IUCLID)
1.190 mg/g Remarks: (IUCLID)
1.290 mg/g Remarks: (IUCLID)
Ratio BOD/ThBOD 60 %
Remarks: (IUCLID)
Bioaccumulative potential
Does not bioaccumulate.
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological information
No data available
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material
must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
IncompatibilitiesReacts with sulfuric acid, oleum, chlorosulfonic acid; strong oxidizing agents; strong bases; chromium trioxide; potassium permanganate; sodium peroxide. Hygroscopic (i.e., absorbs moisture from the air)
Waste DisposalDissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. Alternatively, ethylene glycol can be recovered from polyester plant wastes
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.