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?AGO2 Antibody
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Cat#:PL0502500
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Isotype:Rabbit Polyclonal IgG
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Immunogen:?
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Purification:?Immunogen affinity purified
Storage Buffer:?PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
The Argonaute protein family plays a central role in RNA silencing processes, as essential catalytic components of the RNA-induced silencing complex (RISC). RISC complex is responsible for the gene silencing phenomenon known as RNA interference (RNAi). Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs). Small RNAs guide Argonaute proteins to their specific targets through sequence complementarity (base pairing), which then leads to mRNA cleavage or translation inhibition.
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Alternate Names:
?Q10, AGO2, MGC3183?
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Specificity Reaction:?Hu,Mo, Rat
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Application Notes:?ELISA, WB
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Storage :
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
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This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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