中文名:WYE-354
英文名:WYE-354
英文別名:WYE-354|1062169-56-5|methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate|WYE354|WYE 354|methyl 4-(6-(4-((methoxycarbonyl)amino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine
純度:≥98%
貨號(hào):W128007
包裝:5mg、100mg、25mg
Cas號(hào):1062169-56-5
存儲(chǔ)溫度:-20°C儲(chǔ)存
產(chǎn)品介紹:
WYE-354是ATP競(jìng)爭(zhēng)性mTOR抑制劑,IC50為5 nM,能阻斷mTORC1/P-S6K(T389)和mTORC2/P-AKT(S473),比對(duì)PI3Kα和PI3Kγ的抑制性強(qiáng)100倍和500倍。A potent, specific, and ATP-competitive inhibitor to mTOR with IC50 of 5 nM
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