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Anti-DCC antibody-結(jié)腸直腸癌缺失基因抗體,DCC
  • Anti-DCC antibody-結(jié)腸直腸癌缺失基因抗體,DCC

Anti-DCC antibody-結(jié)腸直腸癌缺失基因抗體

價(jià)格 1138 1880 2900
包裝 50ul 100ul 200ul
最小起訂量 50ul
發(fā)貨地 上海
更新日期 2025-01-10
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產(chǎn)品詳情

中文名稱:Anti-DCC antibody-結(jié)腸直腸癌缺失基因抗體英文名稱:DCC
CAS:538-75-0品牌: 滬震生物
產(chǎn)地: 中國/上海保存條件: -20°C
純度規(guī)格: > 99%產(chǎn)品類別: 抗體 一抗
抗體名: Deleted in Colorectal Cancer; Igdcc1; Immunoglobulin domain cell adhesion molecule; Colorectal cancer related chromosome sequence 18; Colorectal cancer suppressor; CRC 18; CRC18; CRCR 1; CRCR; Deleted in colorectal cancer protein; Deleted in colorectal carcinoma; Netrin receptor DCC; Tumor suppressor protein DCC; DCC_RAT; DCC_HUMAN. 靶點(diǎn): 詳見說明書
宿主: Rabbit適應(yīng)物種: 詳見說明書
克隆性: 詳見說明書濃度: 1mg/ml
應(yīng)用范圍: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.標(biāo)識(shí)物: 詳見說明書
形態(tài): 液體亞型: IgG
免疫原: 詳見說明書貨號(hào): Hz-R22041
用途范圍: 科研使用規(guī)格: 50ul/100ul/200ul
是否進(jìn)口: 是否單克隆: 詳見說明書
保質(zhì)期: 12個(gè)月抗原來源: 詳見說明書
標(biāo)記物: 詳見說明書產(chǎn)品用途: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
2025-01-10 Anti-DCC antibody-結(jié)腸直腸癌缺失基因抗體 DCC 50ul/1138RMB;100ul/1880RMB;200ul/2900RMB 1138 滬震生物 中國/上海 -20°C > 99% 抗體 一抗

Rabbit  Anti-DCC Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:DCC

IR:Immunogen Range:821-920/1461

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:1630

Swiss Prot:P43146

Source:KLH conjugated synthetic peptide derived from human DCC:821-920/1461 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Deleted in colorectal cancer (DCC, chromosome 18q21) was originally identified as a putative tumor suppressor gene that is lost in more than 70% of colorectal cancers. The gene has also been deleted in several other types of cancer. The DCC protein is a type I transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. The extracellular domain is composed of four Ig like domains and six fibronectin type III repeats. Native DCC is found in three isoforms. Two forms, a long and a short isoform, are produced from the same gene but have different initiation sites. The third isoform, produced by alternative splicing, is expressed only in embryonic tissue. Mouse DCC extracellular domain shares 97% and 99% homology with human and rat DCC extracellular domains, respectively. In adults, DCC is highly expressed in the brain but is also expressed at very low levels in multiple normal tissues. In the embyro, high levels of expression are detected in the brain and neural tube. DCC functions as a receptor or a component of a receptor for netrins and mediates the effects of netrins on commissural axons. Netrins are chemoattractants responsible for the guidance of commissural axons at the midline and of motor axons to the their target muscles. DCC induces apoptosis in the absence of ligand binding, blocks apoptosis when engaged by netrin 1, and also acts as a caspase substrate

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)

Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Sheep

image.png
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!

關(guān)鍵字: DCC;Deleted in Colorecta;Igdcc1;CRC18;CRCR 1;CRCR;DCC_RAT;DCC_HUMAN;

公司簡介

上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細(xì)胞,原代細(xì)胞 細(xì)胞培養(yǎng)試劑,常用生化試劑。
成立日期 2014-05-08 (11年) 注冊(cè)資本 100萬元整
員工人數(shù) 10-50人 年?duì)I業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 生化試劑,細(xì)胞培養(yǎng),蛋白組學(xué),分子生物學(xué),細(xì)胞生物學(xué) 經(jīng)營模式 工廠,試劑,定制,服務(wù)
  • 上海滬震實(shí)業(yè)有限公司
VIP 3年
  • 公司成立:11年
  • 注冊(cè)資本:100萬元整
  • 企業(yè)類型:有限責(zé)任公司(國內(nèi)合資)
  • 主營產(chǎn)品:ELISA試劑盒,抗體,細(xì)胞系,原代細(xì)胞,細(xì)胞培養(yǎng)試劑,重組蛋白
  • 公司地址:松江區(qū)
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