Name: Zanubrutinib
CAS#: 1691249-45-2 (S-isomer)
Chemical Formula: C27H29N5O3
Exact Mass: 471.227
Molecular Weight: 471.561
Elemental Analysis: C, 68.77; H, 6.20; N, 14.85; O, 10.18
Description: Zanubrutinib, aslo known as BGB-3111, is a potent and highly selective small molecule BTK inhibitor for the potential treatment of a variety of lymphomas. BGB-3111 selectively binds to and inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. Zanubrutinib has CAS#1691249-45-2 which is the S-isomer.
Synonym: BGB-3111; BGB 3111; BGB3111; Zanubrutinib; Brukinsa.
IUPAC/Chemical Name: (7S)-4,5,6,7-Tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChi Key: RNOAOAWBMHREKO-QFIPXVFZSA-N
InChi Code: InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1
SMILES Code: O=C(C1=C2NCC[C@@H](C3CCN(C(C=C)=O)CC3)N2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
關(guān)鍵字： 贊魯替尼;Zanubrutinib;1691249-45-2;
北京百奧創(chuàng)新科技有限公司是一家專注于生命科學的科技企業(yè)，由在國內(nèi)科研試劑領(lǐng)域有著豐富從業(yè)經(jīng)驗的技術(shù)團隊和管理團隊組建而成，專營進口生物試劑，科學儀器，實驗消耗品等。公司與諸多國外品牌簽下代理，RD、Abcam、CST、Genetex、Biolegend、ebioscience、polypure、polyplus、Bethyl、Novus等，能為廣大科研用戶提供數(shù)萬種試劑、儀器和實驗消耗品。
公司將不斷把上優(yōu)質(zhì)的產(chǎn)品引入國內(nèi)市場，滿足客戶的需求，公司也將緊跟生命科學的發(fā)展，為廣大科研工作者探索生命科學的奧秘奉獻綿薄之力！