中文名稱

羅米地辛

英文名字

Romidepsin

供應商

開曼生物

產(chǎn)品貨號

17130-5

產(chǎn)品報價

￥7207.2/5mg

產(chǎn)品說明書

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購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

Romidepsin, also known as FK228, is a natural bicyclic depsipeptide that, following reduction, selectively inhibits class I histone deacetylases (HDACs).{10790} Reduction of a disulfide bond on romidepsin within the cell generates a zinc-binding thiol, allowing potent inhibition of HDACs 1, 2, 3, and 8 (IC50s = 53, 39, 53, and 26 nM, respectively), with less potency against HDACs 4, 6, 7, and 9 (IC50s = 470, 330, 3,200, and 12,000 nM, respectively).{28023,15938} Through its effects on HDACs, romidepsin has anti-cancer activities, particularly against certain T cell lymphomas.{28022,28021,28020}

產(chǎn)品描述

A natural bicyclic depsipeptide that, following reduction, selectively inhibits class I HDACs (IC50s = 53, 39, 53, and 26 nM, for HDACs 1, 2, 3, and 8, respectively); has anti-cancer activities, particularly against certain T cell lymphomas

保存建議

建議您在收到開曼生物品牌的羅咪酯肽 (5 mg)產(chǎn)品后置于-20℃保存.

其他

開曼生物向全球科學工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應用于腫瘤、氧化氮、神經(jīng)學、凋亡、氧化性損傷、內(nèi)分泌學等不同研究領(lǐng)域.開曼生物可提供用于檢測的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.作為開曼生物在中國的區(qū)域總代理，艾美捷科技有限公司將為中國客戶提供最全面的開曼生物產(chǎn)品以及客戶訂制化服務(wù).