Product Details
| Product Name:
Ribocil |
CAS No.:
1381289-58-2 |
| Purity:
99.71% |
Supply Ability:
10g |
| Release date:
2024/11/08 |
Product Introduction
Bioactivity
| 名稱 | Ribocil |
| 描述 | Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches, strongly inhibiting GFP expression with a 50% effective concentration (EC50: 0.3 μM). |
| 體外活性 | Ribocil is a highly specific bioactive synthetic mimic of FMN, which competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB and inhibits bacterial growth. Ribocil-B shows superior microbiological activity as compared to Ribocil-A (minimum inhibitory concentration (MIC) = 1 μg/ml versus MIC ≥ 64 μg/ml), inhibition of riboflavin synthesis (IC50 = 0.13 μM versus IC50 > 26 μM), and binding affinity to the E. coli FMN aptamer (Kd = 6.6 nM versus Kd ≥ 10,000 nM) [1] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 24.8 mg/mL (64.84 mM)
|
| 關(guān)鍵字 | Inhibitor | Ribocil | Bacterial | inhibit |
| 相關(guān)產(chǎn)品 | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Dimethyl sulfoxide | Crystal Violet |
| 相關(guān)庫(kù) | 高選擇性抑制劑庫(kù) | 經(jīng)典已知活性庫(kù) | 肝臟毒性化合物庫(kù) | NO PAINS 化合物庫(kù) | 抗菌活性庫(kù) | 已知活性化合物庫(kù) | 抗感染化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$51.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-10-31 |
United States