Product Details
| Product Name:
Ribocil-C Racemate |
CAS No.:
2309762-18-1 |
| Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Ribocil-C Racemate |
| Description | Ribocil-C Racemate is the racemate of Ribocil-C, a highly selective inhibitor of bacterial riboflavin riboswitches that control the expression of de novo riboflavin (RF, vitamin B2) biosynthesis in Escherichia coli. |
| In vitro | Ribocil-C, a highly selective inhibitor of the flavin mononucleotide (FMN) riboswitch, effectively regulates the expression of de novo riboflavin (RF, vitamin B2) biosynthesis in Escherichia coli. It specifically targets dual FMN riboswitches to control both RF biosynthesis and uptake processes, critical for the growth and pathogenesis of Staphylococcus aureus. Additionally, Ribocil-C, a small-molecule synthetic FMN analog, binds the FMN riboswitch in various Gram-negative bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii. By inhibiting ribB expression and RF synthesis, it successfully halts bacterial proliferation [1] [2]. |
| In vivo | Treatment with higher doses of Ribocil-C (60 and 120 mg/kg) demonstrated a dose-dependent decrease in bacterial load, with reductions of 1.87 and 3.29 log10 [CFU per g spleen], respectively, compared to the sham-treated mice. No mortality or significant toxicity effects were observed [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 30 mg/mL (71.51 mM)
|
| Keywords | Ribocil-C Racemate | Ribocil C Racemate | RibocilC Racemate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1825355-55-2
$2500.00 / 100mg
-
CAS:755013-59-3
$2580.00 / 50mg
-
CAS:1381289-58-2
$51.00 / 1mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$51.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
|
|
$420.00/1g |
VIP3Y
|
Hebei Dangtong Import and export Co LTD
|
2024-09-13 |
United States