Azosemide NEW
Price | $41 | $58 | $89 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-08 |
Product Details
Product Name: Azosemide | CAS No.: 27589-33-9 |
Purity: 98.93% | Supply Ability: 10g |
Release date: 2024/11/08 |
Product Introduction
Bioactivity
名稱 | Azosemide |
描述 | Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246?μM and 0.197?μM for hNKCC1A and NKCC1B). |
體外活性 | Azosemide inhibits the human sodium-potassium-chloride cotransporter variants hNKCC1B and hNKCC1A [1]. |
體內(nèi)活性 | Azosemide shows a shorter terminal half-life (50.9% decrease) and MRT (64.1% decrease), smaller AUC (81.9% decrease), faster CL (454% increase), CLNR (307% increase) and CLR (853% increase) for NARs [2]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 249 mg/mL (671.44 mM), Sonication is recommended. |
關(guān)鍵字 | Inhibitor | diuretic | Azosemide | sulfonamide | NKCC | NKCC1 | inhibit | hNKCC1A | loop | NKCC1B |
相關(guān)產(chǎn)品 | Furosemide sodium | Torsemide | Bumetanide |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗癌上市藥物庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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