Capmatinib hydrochloride
Price | Get Latest Price | ||
Package | 1kg | 5kg | 10kg |
Min. Order: | 1kg |
Supply Ability: | 1000 |
Update Time: | 2025-01-17 |
Product Details
Product Name: Capmatinib hydrochloride | CAS No.: 1865733-40-9 |
Min. Order: 1kg | Purity: 98 |
Supply Ability: 1000 | Release date: 2025/01/17 |
Product Name: Capmatinib hydrochloride
Synonyms: Capmatinib hydrochloride;Capmatinib hydrochloride Hydrate;Capmatinib HCl hydrate (INCB-28060;Capmatinib 2HCl.H2O;INC-280 2HCl.H2O;INCB28060 2HCl.H2O;NVP-INC280 2HCl.H2O;Capmatinib Hydrochloride Hydrate (INCB28060)
CAS: 1865733-40-9
MF: C23H20ClFN6O2
MW: 466.9
Capmatinib dihydrochloride hydrate is a orally active,reversible MET tyrosine kinase inhibitor that received approval for advanced non-small cell lung cancer(NSCLC) harboring MET exon 14 skipping mutationa. Capmatinib dihydrochloride hydrate can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib dihydrochloride hydrate potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib dihydrochloride hydrate is largely metabolized by CYP3A4 and aldehyde oxidase
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- Since: 2024-03-12
- Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La