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Postion:Product Catalog >Biochemical Engineering>Inhibitors>protein tyrosine kinase>Capmatinib hydrochloride
Capmatinib hydrochloride
  • Capmatinib hydrochloride
  • Capmatinib hydrochloride
  • Capmatinib hydrochloride

Capmatinib hydrochloride

Price Get Latest Price
Package 1kg 5kg 10kg
Min. Order: 1kg
Supply Ability: 1000
Update Time: 2025-01-17

Product Details

Product Name: Capmatinib hydrochloride CAS No.: 1865733-40-9
Min. Order: 1kg Purity: 98
Supply Ability: 1000 Release date: 2025/01/17

Product Name:    Capmatinib hydrochloride

Synonyms:    Capmatinib hydrochloride;Capmatinib hydrochloride Hydrate;Capmatinib HCl hydrate (INCB-28060;Capmatinib 2HCl.H2O;INC-280 2HCl.H2O;INCB28060 2HCl.H2O;NVP-INC280 2HCl.H2O;Capmatinib Hydrochloride Hydrate (INCB28060)

CAS:    1865733-40-9

MF:    C23H20ClFN6O2

MW:    466.9

Capmatinib dihydrochloride hydrate is a orally active,reversible MET tyrosine kinase inhibitor that received approval for advanced non-small cell lung cancer(NSCLC) harboring MET exon 14 skipping mutationa. Capmatinib dihydrochloride hydrate can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib dihydrochloride hydrate potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib dihydrochloride hydrate is largely metabolized by CYP3A4 and aldehyde oxidase


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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