成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Biochemical Engineering>Inhibitors>protein tyrosine kinase>Capmatinib 2HCl.H2O
Capmatinib 2HCl.H2O
  • Capmatinib 2HCl.H2O

Capmatinib 2HCl.H2O NEW

Price $45 $63 $117
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Capmatinib 2HCl.H2O CAS No.: 1865733-40-9
Purity: 99.84% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCapmatinib 2HCl.H2O
DescriptionCapmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.
In vitroCapmatinib was found to be highly selective for MET over other kinases.?It was active against cancer models that are characterized by MET amplification, marked MET overexpression, MET exon 14 skipping mutations, or MET activation via expression of the ligand hepatocyte growth factor (HGF)[1].
In vivoIn cancer models where MET is the dominant oncogenic driver, anticancer activity could be further enhanced by combination treatments, for example, by the addition of apoptosis-inducing BH3 mimetics.?The combinations of capmatinib and other kinase inhibitors resulted in enhanced anticancer activity against models where MET activation co-occurred with other oncogenic drivers, for example EGFR activating mutations[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 30 mg/mL (59.6 mM)
KeywordsS114 | SNU-5 | Capmatinib 2HCl.H2O | ATP competitive | Balb/c nu/nu mice | U-87MG | INCB-28060 dihydrochloride | orally active | Capmatinib dihydrochloride | Capmatinib 2HCl.H-2O | INC280 dihydrochloride | Apoptosis | inhibit | Inhibitor | c-Met/HGFR | H441
Inhibitors RelatedCabozantinib | Capmatinib 2HCl | SGI-7079 | (±)-Norcantharidin | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Amuvatinib | Norcantharidin | Cabozantinib S-malate | Capmatinib xHCl | Bacitracin Zinc | Capmatinib
Related Compound LibrariesBioactive Compound Library | Tyrosine Kinase Inhibitor Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Kinase Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$0.00/1g
VIP1Y
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
2024-11-04
$0.00/1kg
VIP1Y
Fuzhou Lista Biotechnology Co.,Ltd
2024-07-26
$1.00/1kg
VIP2Y
Jinan Million Pharmaceutical Co., Ltd
2023-12-11
$0.00/25kg
VIP6Y
Zison Pharmaceutical (Shandong) Co., Ltd.
2023-07-22
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY