7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Price | $1 |
Package | 1g |
Min. Order: | 1g |
Supply Ability: | g/kg/Ton |
Update Time: | 2019-12-26 |
Product Details
Product Name: 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid | CAS No.: 147059-75-4 |
Min. Order: 1g | Purity: ≥98% |
Supply Ability: g/kg/Ton | Release date: 2019/12/26 |
Delivery Time: Prompt | Packaging: Bottle/Durm/Bag |
Transportation: By air/Bay Sea/Express |
Heidi 0725
Email:heidi@coreychem.com
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7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Basic information
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Product Name:
7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Synonyms:
Trovafloxacin mesylate - CP 99219 mesylate;Trovafloxacin Methanesulfonate;Trovafloxacin MonoMeth;(1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate;7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;Trovafloxacin monomethanesulfonate;Trovan;Unii-0p1lko80wn
CAS:
147059-75-4
MF:
C20H15F3N4O3
MW:
0
EINECS:
Product Categories:
Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pfizer compounds;Pharmaceuticals
Mol File:
147059-75-4.mol
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7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Chemical Properties
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Melting point
>250°C (dec.)
storage temp.
Desiccate at RT
solubility
DMSO: >10mg/mL
form
powder
color
white to off-white
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Safety Information
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Hazard Codes
C
Risk Statements
63-34
Safety Statements
26-36-45
RIDADR
UN 1759 8 / PGIII
WGK Germany
3
RTECS
QN2791250
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MSDS Information
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7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid Usage And Synthesis
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Chemical Properties
White Solid
Uses
Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.
Definition
ChEBI: A methanesulfonate (mesylate) salt prepared from equimolar amounts of trovafloxacin and methanesulfonic acid. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure.
Brand name
Trovan (Pfizer).
Biological Activity
Fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis. Displays potent activity against gram-positive and gram-negative bacteria.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates:
Pharmaceutical intermediates;
OLED intermediates;
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- Since: 2014-12-17
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