TG4-155
- $62 - $5328
- Product name: TG4-155
- CAS: 1164462-05-8
- MF: C23H26N2O4
- MW: 394.46
- EINECS:
- MDL Number:MFCD03829939
- Synonyms:TG4-155;(E)-N-(2-(2-Methyl-1H-indol-1-yl)ethyl)-3-(3,4,5-trimethoxyphenyl)acrylamide;TG4-155; TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155;(2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide;2-Propenamide, N-[2-(2-methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-, (2E)-;inhibit,TG4-155,TG-4-155,TG4155,TG4 155,Prostaglandin Receptor,Inhibitor
23 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- ManufacturerAK Scientific
- Product numberSYN5120
- Product descriptionTG4-155
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberBRS0009230
- Product descriptionTG4-155 95.00%
- Packaging5MG
- Price$459.22
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5279
- Product descriptionTG4-155
- Packaging5mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5279
- Product descriptionTG4-155
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573466
- Product descriptionTG4-155 >98%
- Packaging100mg
- Price$838.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573466
- Product descriptionTG4-155 >98%
- Packaging250mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573466
- Product descriptionTG4-155 >98%
- Packaging1g
- Price$2839
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17639
- Product descriptionTG4-155 ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17639
- Product descriptionTG4-155 ≥98%
- Packaging10mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17639
- Product descriptionTG4-155
- Packaging25mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17639
- Product descriptionTG4-155
- Packaging50mg
- Price$448
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0014805
- Product descriptionTG4-155 99.12%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0014805
- Product descriptionTG4-155 99.12%
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0014805
- Product descriptionTG4-155 99.12%
- Packaging25mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0014805
- Product descriptionTG4-155 99.12%
- Packaging50mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0014805
- Product descriptionTG4-155 99.12%
- Packaging100mg
- Price$880
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5120 | TG4-155 | 10mg | $130 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | BRS0009230 | TG4-155 95.00% | 5MG | $459.22 | 2021-12-16 | Buy |
ApexBio Technology | C5279 | TG4-155 | 5mg | $103 | 2021-12-16 | Buy |
ApexBio Technology | C5279 | TG4-155 | 10mg | $180 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573466 | TG4-155 >98% | 100mg | $838.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573466 | TG4-155 >98% | 250mg | $1431.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573466 | TG4-155 >98% | 1g | $2839 | 2021-12-16 | Buy |
Cayman Chemical | 17639 | TG4-155 ≥98% | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 17639 | TG4-155 ≥98% | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 17639 | TG4-155 | 25mg | $239 | 2024-03-01 | Buy |
Cayman Chemical | 17639 | TG4-155 | 50mg | $448 | 2024-03-01 | Buy |
ChemScene | CS-0014805 | TG4-155 99.12% | 5mg | $80 | 2021-12-16 | Buy |
ChemScene | CS-0014805 | TG4-155 99.12% | 10mg | $130 | 2021-12-16 | Buy |
ChemScene | CS-0014805 | TG4-155 99.12% | 25mg | $280 | 2021-12-16 | Buy |
ChemScene | CS-0014805 | TG4-155 99.12% | 50mg | $490 | 2021-12-16 | Buy |
ChemScene | CS-0014805 | TG4-155 99.12% | 100mg | $880 | 2021-12-16 | Buy |
Properties
Boiling point :641.3±55.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 10 mg/ml).
pka :14.04±0.46(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 10 mg/ml).
pka :14.04±0.46(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
Prostaglandin E2 (PGE2) evokes distinct responses through four different ‘E prostanoid’ (EP) receptors. EP2 is a G protein-coupled receptor that has diverse roles, including those in cancer, inflammation, and neuroprotection. TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 μM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells treated with the selective EP2 agonist butaprost alone or with LPS and IFNγ. TG4-155 significantly reduces neurodegeneration in a mouse model of status epilepticus, induced by pilocarpine . It inhibits proliferation, invasion, and inflammatory cytokine expression in cancer cells treated with butaprost.More related product prices
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