(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
![(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT price.](/CAS/GIF/115104-28-4.gif)
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- $32 - $860
- Product name: (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
- CAS: 115104-28-4
- MF: C26H27ClN2O3S2
- MW: 515.09
- EINECS:
- MDL Number:MFCD00797675
- Synonyms:MK-571 SODIUM SALT;MK-571, NA SALT;3-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic Acid Sodium Salt;3-[[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid;L-660711;(3-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-dimethylamino-3-oxopropyl)thio)methyl)thiopropanoic acid;Mk 0571;Mk 0679
16 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5MG
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number8643CN
- Product descriptionVerlukast
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8643CN
- Product descriptionVerlukast
- Packaging10mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0318824
- Product description(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00%
- Packaging1MG
- Price$563.93
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0318824
- Product description(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00%
- Packaging5MG
- Price$658.12
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0318824
- Product description(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00%
- Packaging10MG
- Price$691.27
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7023
- Product descriptionMK-571
- Packaging50mg
- Price$608
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10029
- Product descriptionMK-571 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10029
- Product descriptionMK-571 ≥95%
- Packaging5mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10029
- Product descriptionMK-571 ≥95%
- Packaging10mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10029
- Product descriptionMK-571 ≥95%
- Packaging50mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number12363
- Product descriptionMK-571
- Packaging10mg
- Price$860
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2338
- Product descriptionMK571
- Packaging10
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM424500
- Product descriptionMK-571
- Packaging1mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM424500
- Product descriptionMK-571
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number045035
- Product descriptionMK-571 sodium salt
- Packaging5mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255833
- Product descriptionMK 571
- Packaging10mg
- Price$446
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8643CN | Verlukast | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 8643CN | Verlukast | 10mg | $232 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0318824 | (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00% | 1MG | $563.93 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0318824 | (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00% | 5MG | $658.12 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0318824 | (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID SODIUM SALT 95.00% | 10MG | $691.27 | 2021-12-16 | Buy |
| ApexBio Technology | B7023 | MK-571 | 50mg | $608 | 2021-12-16 | Buy |
| Cayman Chemical | 10029 | MK-571 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10029 | MK-571 ≥95% | 5mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 10029 | MK-571 ≥95% | 10mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 10029 | MK-571 ≥95% | 50mg | $533 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 12363 | MK-571 | 10mg | $860 | 2021-12-16 | Buy |
| Tocris | 2338 | MK571 | 10 | $195 | 2021-12-16 | Buy |
| TRC | M424500 | MK-571 | 1mg | $45 | 2021-12-16 | Buy |
| TRC | M424500 | MK-571 | 5mg | $60 | 2021-12-16 | Buy |
| Usbiological | 045035 | MK-571 sodium salt | 5mg | $290 | 2021-12-16 | Buy |
| Usbiological | 255833 | MK 571 | 10mg | $446 | 2021-12-16 | Buy |
Properties
Melting point :65-70°C
Boiling point :712.3±60.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :4.27±0.10(Predicted)
form :Off-white solid.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :712.3±60.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :4.27±0.10(Predicted)
form :Off-white solid.
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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Description
The cysteinyl leukotrienes (CysLTs), leukotriene (LTC4), LTD4, and LTE4, mediate their actions through two distinct G protein-coupled receptors. LTD4 is the preferred ligand for the CysLT1 receptor, whereas LTC4 and LTD4 bind with approximately equal affinity to the CysLT2 receptor. MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively, which is indicative of CysLT1 receptor-mediated activity in these preparations. MK-571 effectively blocks LTD4 activation of recombinant human and murine CysLT1 receptors but is ineffective at blocking LTC4 or LTD4 activation of the recombinant human or murine CysLT2 receptors.More related product prices
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