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ChemicalBook >> CAS DataBase List >> BAY 11-7085

BAY 11-7085

BAY 11-7085 price.
  • $50 - $5744
  • Product name: BAY 11-7085
  • CAS: 196309-76-9
  • MF: C13H15NO2S
  • MW: 249.33
  • EINECS:
  • MDL Number:MFCD01862602
  • Synonyms:BAY 117083 (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile;(2E)-3-[[4-(1,1-DIMETHYLETHYL)PHENYL]SULFONYL]-2-PROPENENITRILE;(E)-3-(T-BUTYLPHENYLSULFONYL)-2-PROPENENITRILE;(E)3-[(4-T-BUTYLPHENYL)SULFONYL]-2-PROPENENITRILE;BAY 11-7085;(E)-3-(4-tert-butylphenylsulfonyl)acrylonitrile;BAY 117083;(2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile BAY 11-7085
30 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 25mg
  • 100MG
  • 250mg
  • 1g
  • 10
  • 5MG
  • 10mg
  • 50mg
  • 5g
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA0073SR
  • Product description(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N)
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0073SR
  • Product description(E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N)
  • Packaging50mg
  • Price$444
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1192
  • Product description(E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile
  • Packaging5g
  • Price$5744
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67222
  • Product descriptionBAY 11-7085, 99%
  • Packaging10mg
  • Price$169
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000108
  • Product descriptionBAY 11-7085 95.00%
  • Packaging5MG
  • Price$168.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000108
  • Product descriptionBAY 11-7085 95.00%
  • Packaging10MG
  • Price$685.21
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3033
  • Product descriptionBAY 11-7085
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60307
  • Product descriptionBAY 11-7085
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14795
  • Product descriptionBAY 11-7085 ≥98%
  • Packaging5mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14795
  • Product descriptionBAY 11-7085 ≥98%
  • Packaging10mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14795
  • Product descriptionBAY 11-7085 ≥98%
  • Packaging25mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14795
  • Product descriptionBAY 11-7085 ≥98%
  • Packaging50mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number42195
  • Product descriptionBAY11-7085,≥98%(HPLC) ≥98%(HPLC)
  • Packaging10MG
  • Price$110.66
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number42195
  • Product descriptionBAY11-7085,98%(HPLC) 98%(HPLC)
  • Packaging100MG
  • Price$720.16
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6316
  • Product descriptionBAY 11-7085 99.99%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6316
  • Product descriptionBAY 11-7085 99.99%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0073SR (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N) 10mg $99 2021-12-16 Buy
aablocks AA0073SR (E)-3-((4-(tert-Butyl)phenyl)sulfonyl)acrylonitrile >97.0%(N) 50mg $444 2021-12-16 Buy
AK Scientific Y1192 (E)-3-(4-tert-butylphenyl)sulfonylprop-2-enenitrile 5g $5744 2021-12-16 Buy
Alfa Aesar J67222 BAY 11-7085, 99% 10mg $169 2023-06-20 Buy
American Custom Chemicals Corporation INB0000108 BAY 11-7085 95.00% 5MG $168.3 2021-12-16 Buy
American Custom Chemicals Corporation INB0000108 BAY 11-7085 95.00% 10MG $685.21 2021-12-16 Buy
ApexBio Technology B3033 BAY 11-7085 10mM(in 1mL DMSO) $60 2021-12-16 Buy
Arctom CFN60307 BAY 11-7085 10mg $168 2021-12-16 Buy
Cayman Chemical 14795 BAY 11-7085 ≥98% 5mg $57 2024-03-01 Buy
Cayman Chemical 14795 BAY 11-7085 ≥98% 10mg $89 2024-03-01 Buy
Cayman Chemical 14795 BAY 11-7085 ≥98% 25mg $208 2024-03-01 Buy
Cayman Chemical 14795 BAY 11-7085 ≥98% 50mg $384 2024-03-01 Buy
Chem-Impex 42195 BAY11-7085,≥98%(HPLC) ≥98%(HPLC) 10MG $110.66 2021-12-16 Buy
Chem-Impex 42195 BAY11-7085,98%(HPLC) 98%(HPLC) 100MG $720.16 2021-12-16 Buy
ChemScene CS-6316 BAY 11-7085 99.99% 5mg $50 2021-12-16 Buy
ChemScene CS-6316 BAY 11-7085 99.99% 10mg $70 2021-12-16 Buy

Properties

Melting point :80-82℃
Boiling point :407.1±45.0 °C(Predicted)
Density :1.144
Flash point :200℃
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >25 mg/mL, soluble
form :solid
color :white
Sensitive :Light Sensitive
InChIKey :VHKZGNPOHPFPER-ONNFQVAWSA-N
CAS DataBase Reference :196309-76-9

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

In the classical pathway of NF-κB activation, phosphorylation of the inhibitor of NF-κB (IκBα) releases the inhibitor from NF-κB, allowing IκBα degradation and NF-κB activation and nuclear import. BAY-11-7085 is an irreversible inhibitor of IκBα phosphorylation, preventing activation of NF-κB by cytokines and lipopolysaccharide (IC50 = 10 μM). It blocks gene expression that is regulated through the classical pathway of NF-κB activation and in this way blocks apoptosis, cell adhesion, and inflammation. BAY-11-7085 is also used to study IκBα actions that are independent of NF-κB signaling.

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