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ChemicalBook >> CAS DataBase List >> AR7

AR7

AR7 price.
  • $32 - $1350
  • Product name: AR7
  • CAS: 80306-38-3
  • MF: C15H12ClNO
  • MW: 257.71
  • EINECS:
  • MDL Number:MFCD27978377
  • Synonyms:AR7;7-Chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine;7-Chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine;Atypical retinoid 7;Thyroid Hormone receptor,α1 human;c-ERBA-1;ERBA;ERB-T-1
21 prices
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5μG
  • 10μG
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2988DF
  • Product description7-Chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine
  • Packaging5mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA857996
  • Product description7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+%
  • Packaging50mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA857996
  • Product description7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+%
  • Packaging25mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA857996
  • Product description7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+%
  • Packaging10mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA857996
  • Product description7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+%
  • Packaging5mg
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22946
  • Product descriptionAR-7
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22946
  • Product descriptionAR-7
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22946
  • Product descriptionAR-7
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22946
  • Product descriptionAR-7
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6249
  • Product descriptionAR7 99.70%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6249
  • Product descriptionAR7 99.70%
  • Packaging50mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22084
  • Product descriptionAR-7
  • Packaging25mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22084
  • Product descriptionAR-7
  • Packaging50mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10135
  • Product descriptionAR-7 >98%
  • Packaging1g
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSRP2046
  • Product descriptionThyroid Hormone receptor,α1 human recombinant, expressed in insect cells, ≥80% (SDS-PAGE)
  • Packaging5μG
  • Price$471
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSRP2127
  • Product descriptionTR, α1, GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE)
  • Packaging10μG
  • Price$400
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2988DF 7-Chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine 5mg $124 2021-12-16 Buy
Ambeed A857996 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+% 50mg $201 2021-12-16 Buy
Ambeed A857996 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+% 25mg $154 2021-12-16 Buy
Ambeed A857996 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+% 10mg $118 2021-12-16 Buy
Ambeed A857996 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine 98+% 5mg $71 2021-12-16 Buy
Cayman Chemical 22946 AR-7 1mg $32 2024-03-01 Buy
Cayman Chemical 22946 AR-7 5mg $100 2024-03-01 Buy
Cayman Chemical 22946 AR-7 10mg $184 2024-03-01 Buy
Cayman Chemical 22946 AR-7 25mg $420 2024-03-01 Buy
ChemScene CS-6249 AR7 99.70% 5mg $72 2021-12-16 Buy
ChemScene CS-6249 AR7 99.70% 50mg $432 2021-12-16 Buy
CSNpharm CSN22084 AR-7 25mg $224 2021-12-16 Buy
CSNpharm CSN22084 AR-7 50mg $367 2021-12-16 Buy
DC Chemicals DC10135 AR-7 >98% 1g $1350 2021-12-16 Buy
Sigma-Aldrich SRP2046 Thyroid Hormone receptor,α1 human recombinant, expressed in insect cells, ≥80% (SDS-PAGE) 5μG $471 2024-03-01 Buy
Sigma-Aldrich SRP2127 TR, α1, GST tagged human recombinant, expressed in E. coli, ≥70% (SDS-PAGE) 10μG $400 2024-03-01 Buy

Properties

storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
biological source :human
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

AR7 (80306-38-3) is an atypical retinoid which acts as an RARα antagonist and activates chaperone-mediated autophagy (CMA) via an RAR-dependent pathway.1 Downstream signaling results in an increase of LAMP-2A expression.1 Cells pretreated with AR7 had markedly improved viability in a paraquat-induced oxidative stress model.1 AR7 stimulated CMA and attenuated accumulation of SNCA oligomers in prolonged cultures of mutant cortical neurons2 indicating that CMA activation may be a viable disease modifying strategy in Parkinson’s disease3. A targetome analysis of AR7-induced CMA in cancer cells has been performed.4